Protein microchip bioassay with dual fluorescent- and MALDI read-out.
(2005) 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences p.466-468- Abstract
- Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundance proteins while low signaling proteins are highly suppressed. Protein microarrays have a potential to speed up the discovery of new markers and targets of interest to the pharmaceutical industry. The technique is also readily compatible with high-throughput applications.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1406260
- author
- Finnskog, David LU ; Ressine, Anton LU ; Laurell, Thomas LU and Marko-Varga, György LU
- organization
- publishing date
- 2005
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- fluorescence readout, MALDI-TOF read-out, immunoassay
- host publication
- Micro Total Analysis Systems 2004, Vol 1
- issue
- 296
- pages
- 466 - 468
- publisher
- Springer
- conference name
- 8th International Conference on Miniaturized Systems for Chemistry and Life Sciences
- conference location
- Malmo, Sweden
- conference dates
- 2004-09-26 - 2004-09-30
- external identifiers
-
- wos:000228997000156
- ISSN
- 0260-6291
- language
- English
- LU publication?
- yes
- id
- 56058b2a-5c2c-4075-9219-b97a83d2f611 (old id 1406260)
- date added to LUP
- 2016-04-01 16:47:17
- date last changed
- 2018-11-21 20:44:13
@inproceedings{56058b2a-5c2c-4075-9219-b97a83d2f611, abstract = {{Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundance proteins while low signaling proteins are highly suppressed. Protein microarrays have a potential to speed up the discovery of new markers and targets of interest to the pharmaceutical industry. The technique is also readily compatible with high-throughput applications.}}, author = {{Finnskog, David and Ressine, Anton and Laurell, Thomas and Marko-Varga, György}}, booktitle = {{Micro Total Analysis Systems 2004, Vol 1}}, issn = {{0260-6291}}, keywords = {{fluorescence readout; MALDI-TOF read-out; immunoassay}}, language = {{eng}}, number = {{296}}, pages = {{466--468}}, publisher = {{Springer}}, title = {{Protein microchip bioassay with dual fluorescent- and MALDI read-out.}}, year = {{2005}}, }