SANS study of the interactions among DNA, a cationic surfactant, and polystyrene latex particles
(2005) In Langmuir 21(8). p.3578-3583- Abstract
- The compaction of DNA by a cationic surfactant both in the bulk and adsorbed on the surface of latex particles was followed for the first time by SANS. In the bulk, a decrease in the overall size of the DNA coil in the presence of the cationic surfactant was observed at a negative-to-positive charge ratio far below the phase separation region, at a negative-to-positive charge ratio of 18. Additionally, large surfactant aggregates seem to form within the DNA-surfactant complex. On the other hand, DNA adsorbs onto the surface of latex particles, forming a thick layer, as evidenced by the fitting of the SANS data to a core-shell form factor. Addition of a cationic surfactant to the DNA-coated latex particles at a negative-to-positive charge... (More)
- The compaction of DNA by a cationic surfactant both in the bulk and adsorbed on the surface of latex particles was followed for the first time by SANS. In the bulk, a decrease in the overall size of the DNA coil in the presence of the cationic surfactant was observed at a negative-to-positive charge ratio far below the phase separation region, at a negative-to-positive charge ratio of 18. Additionally, large surfactant aggregates seem to form within the DNA-surfactant complex. On the other hand, DNA adsorbs onto the surface of latex particles, forming a thick layer, as evidenced by the fitting of the SANS data to a core-shell form factor. Addition of a cationic surfactant to the DNA-coated latex particles at a negative-to-positive charge ratio of 38 induces a slight decrease in the size of the particle layer, where the cationic surfactant is evenly distributed within the adsorbed layer. A further decrease of the negative-to-positive charge ratio to 18 induces a dramatic change in the SANS data that suggests significant compaction of the adsorbed layer and the formation of large surfactant aggregates, similar to those detected in the bulk. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/157240
- author
- Cárdenas, Marité LU ; Dreiss, C A ; Nylander, Tommy LU ; Chan, C P ; Cosgrove, T and Lindman, Björn LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Langmuir
- volume
- 21
- issue
- 8
- pages
- 3578 - 3583
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- wos:000228218700054
- pmid:15807604
- scopus:17444394006
- ISSN
- 0743-7463
- DOI
- 10.1021/la047251w
- language
- English
- LU publication?
- yes
- id
- 71ca64a4-8162-4b91-a7bc-257c9deb4475 (old id 157240)
- date added to LUP
- 2016-04-01 12:08:29
- date last changed
- 2022-01-26 23:25:12
@article{71ca64a4-8162-4b91-a7bc-257c9deb4475, abstract = {{The compaction of DNA by a cationic surfactant both in the bulk and adsorbed on the surface of latex particles was followed for the first time by SANS. In the bulk, a decrease in the overall size of the DNA coil in the presence of the cationic surfactant was observed at a negative-to-positive charge ratio far below the phase separation region, at a negative-to-positive charge ratio of 18. Additionally, large surfactant aggregates seem to form within the DNA-surfactant complex. On the other hand, DNA adsorbs onto the surface of latex particles, forming a thick layer, as evidenced by the fitting of the SANS data to a core-shell form factor. Addition of a cationic surfactant to the DNA-coated latex particles at a negative-to-positive charge ratio of 38 induces a slight decrease in the size of the particle layer, where the cationic surfactant is evenly distributed within the adsorbed layer. A further decrease of the negative-to-positive charge ratio to 18 induces a dramatic change in the SANS data that suggests significant compaction of the adsorbed layer and the formation of large surfactant aggregates, similar to those detected in the bulk.}}, author = {{Cárdenas, Marité and Dreiss, C A and Nylander, Tommy and Chan, C P and Cosgrove, T and Lindman, Björn}}, issn = {{0743-7463}}, language = {{eng}}, number = {{8}}, pages = {{3578--3583}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Langmuir}}, title = {{SANS study of the interactions among DNA, a cationic surfactant, and polystyrene latex particles}}, url = {{http://dx.doi.org/10.1021/la047251w}}, doi = {{10.1021/la047251w}}, volume = {{21}}, year = {{2005}}, }