Kinin System Activation in Vasculitis.
Kahn, Robin LU and Karpman, Diana LU
(2011)
In Acta paediatrica
100(7).
p.950-957
- Abstract
- Vasculitis is a systemic autoimmune inflammatory disease, characterized by inflammation in and around vessel walls leading to perturbed vessel patency and tissue damage. Many different organs may be involved. In this review pathogenetic mechanisms of vasculitis are discussed, with special reference to activation of the kinin system. Mechanisms of kinin system activation are described ultimately leading to release of kinins from high-molecular-weight-kininogen. These vasoactive peptides promote inflammation. Conclusion: Kinin system activation during vasculitis promotes inflammation.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1883999
- author
- Kahn, Robin
LU
and Karpman, Diana
LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Children, Bradykinin, Kinin receptors, Proteinase 3, Vasculitis
- in
- Acta paediatrica
- volume
- 100
- issue
- 7
- pages
- 950 - 957
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000291224200019
- pmid:21401717
- scopus:79958036673
- pmid:21401717
- ISSN
- 1651-2227
- DOI
- 10.1111/j.1651-2227.2011.02266.x
- language
- English
- LU publication?
- yes
- id
- 1bb53ea7-e959-4ff9-ae8a-2d9f61975955 (old id 1883999)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/21401717?dopt=Abstract
- date added to LUP
- 2016-04-01 13:04:19
- date last changed
- 2022-01-27 17:06:39
@article{1bb53ea7-e959-4ff9-ae8a-2d9f61975955,
abstract = {{Vasculitis is a systemic autoimmune inflammatory disease, characterized by inflammation in and around vessel walls leading to perturbed vessel patency and tissue damage. Many different organs may be involved. In this review pathogenetic mechanisms of vasculitis are discussed, with special reference to activation of the kinin system. Mechanisms of kinin system activation are described ultimately leading to release of kinins from high-molecular-weight-kininogen. These vasoactive peptides promote inflammation. Conclusion: Kinin system activation during vasculitis promotes inflammation.}},
author = {{Kahn, Robin and Karpman, Diana}},
issn = {{1651-2227}},
keywords = {{Children; Bradykinin; Kinin receptors; Proteinase 3; Vasculitis}},
language = {{eng}},
number = {{7}},
pages = {{950--957}},
publisher = {{Wiley-Blackwell}},
series = {{Acta paediatrica}},
title = {{Kinin System Activation in Vasculitis.}},
url = {{http://dx.doi.org/10.1111/j.1651-2227.2011.02266.x}},
doi = {{10.1111/j.1651-2227.2011.02266.x}},
volume = {{100}},
year = {{2011}},
}