Relation Between Growth And Bone Collagen Content In Young Pigs; Effects Of Dietary Alpha-Ketoglutarate Supplementation
(2011) In Bulletin of the Veterinary Institute in Puławy 55(2). p.287-292- Abstract
- The aim of this study was to determine the effect of dietary supplementation with alpha-ketoglutarate (AKG) sodium salt on growth rate in relation to bone collagen formation during the first 70 d of postnatal life in piglets. The results show that dietary AKG supplementation increased body weight of the experimental piglets in comparison to the controls, especially between 21(st) and 56(th) d of life (P <= 0.01). Moreover, the area of collagen trabeculae slightly increased in experimental age sub-groups and reached the highest differences between 14(th) (P <= 0.01) and 70(th) d of piglets life (P <= 0.001). In contrast, the highest values for the number of collagen trabeculae were observed in piglets at 3(rd) d of age, regardless... (More)
- The aim of this study was to determine the effect of dietary supplementation with alpha-ketoglutarate (AKG) sodium salt on growth rate in relation to bone collagen formation during the first 70 d of postnatal life in piglets. The results show that dietary AKG supplementation increased body weight of the experimental piglets in comparison to the controls, especially between 21(st) and 56(th) d of life (P <= 0.01). Moreover, the area of collagen trabeculae slightly increased in experimental age sub-groups and reached the highest differences between 14(th) (P <= 0.01) and 70(th) d of piglets life (P <= 0.001). In contrast, the highest values for the number of collagen trabeculae were observed in piglets at 3(rd) d of age, regardless of treatment group. The positive effect of AKG supplementation on the number of collagen trabeculae was found between 3(rd) and 35(th) d of life, with statistical confirmation at days 14, 35, and 56 (P <= 0.01). The data-lines of the bone strain showed similar course during the whole experimental period, except 56(th) d of life, when the experimental piglets reached statistically significant, higher values in comparison to the controls (P <= 0.05). Similarly, the blood plasma osteocalcin reached the highest concentration in experimental sub-groups from 21(st) d of life in comparison to the controls, with statistical significance at the age of 56 (P <= 0.05). These data indicate that dietary AKG supplementation effectively stimulated collagen synthesis in young growing piglets, both before and after weaning. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2029086
- author
- Kowalik, Sylwester ; Wawrzyniak-Gacek, Agata ; Piersiak, Tomasz and Pierzynowski, Stefan LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- piglets, bone, collagen, alpha-ketoglutarate
- in
- Bulletin of the Veterinary Institute in Puławy
- volume
- 55
- issue
- 2
- pages
- 287 - 292
- publisher
- National Veterinary Research Institute
- external identifiers
-
- wos:000292488900021
- scopus:79960786780
- ISSN
- 0042-4870
- language
- English
- LU publication?
- yes
- id
- 1cf63387-b451-4408-b118-1b2e7dc77bef (old id 2029086)
- alternative location
- http://bulletin.piwet.pulawy.pl/images/stories/pdf/20112/20112287292.pdf
- date added to LUP
- 2016-04-01 13:46:05
- date last changed
- 2022-02-04 17:17:15
@article{1cf63387-b451-4408-b118-1b2e7dc77bef,
abstract = {{The aim of this study was to determine the effect of dietary supplementation with alpha-ketoglutarate (AKG) sodium salt on growth rate in relation to bone collagen formation during the first 70 d of postnatal life in piglets. The results show that dietary AKG supplementation increased body weight of the experimental piglets in comparison to the controls, especially between 21(st) and 56(th) d of life (P <= 0.01). Moreover, the area of collagen trabeculae slightly increased in experimental age sub-groups and reached the highest differences between 14(th) (P <= 0.01) and 70(th) d of piglets life (P <= 0.001). In contrast, the highest values for the number of collagen trabeculae were observed in piglets at 3(rd) d of age, regardless of treatment group. The positive effect of AKG supplementation on the number of collagen trabeculae was found between 3(rd) and 35(th) d of life, with statistical confirmation at days 14, 35, and 56 (P <= 0.01). The data-lines of the bone strain showed similar course during the whole experimental period, except 56(th) d of life, when the experimental piglets reached statistically significant, higher values in comparison to the controls (P <= 0.05). Similarly, the blood plasma osteocalcin reached the highest concentration in experimental sub-groups from 21(st) d of life in comparison to the controls, with statistical significance at the age of 56 (P <= 0.05). These data indicate that dietary AKG supplementation effectively stimulated collagen synthesis in young growing piglets, both before and after weaning.}},
author = {{Kowalik, Sylwester and Wawrzyniak-Gacek, Agata and Piersiak, Tomasz and Pierzynowski, Stefan}},
issn = {{0042-4870}},
keywords = {{piglets; bone; collagen; alpha-ketoglutarate}},
language = {{eng}},
number = {{2}},
pages = {{287--292}},
publisher = {{National Veterinary Research Institute}},
series = {{Bulletin of the Veterinary Institute in Puławy}},
title = {{Relation Between Growth And Bone Collagen Content In Young Pigs; Effects Of Dietary Alpha-Ketoglutarate Supplementation}},
url = {{http://bulletin.piwet.pulawy.pl/images/stories/pdf/20112/20112287292.pdf}},
volume = {{55}},
year = {{2011}},
}