Influence of alpha-ketoglutarate on bone mineral density of the femur in piglets
(2005) In Bulletin of the Veterinary Institute in Puławy 49(3). p.343-348- Abstract
- The aim of this study was to determine the influence of daily oral administration of alpha-ketoglutarate (AKG) on bone mineral density of the femur and concentration of 17-beta-oestradiol in blood plasma during 70 d of postnatal life in piglets. All the animals were kept under standard rearing conditions. AKG was administered orally from the 1(st) d of life, while the control piglets were treated in the same way and time with physiological saline. The experimental and control groups were assigned to 6 age subgroups: 3, 14, 21, 35, 56 and 70 d of life. The animals from both groups were euthanised, then bone samples were collected and frozen at -25 degrees C until further analyses. Using dual-energy x-ray absorptiometry (DEXA method) bone... (More)
- The aim of this study was to determine the influence of daily oral administration of alpha-ketoglutarate (AKG) on bone mineral density of the femur and concentration of 17-beta-oestradiol in blood plasma during 70 d of postnatal life in piglets. All the animals were kept under standard rearing conditions. AKG was administered orally from the 1(st) d of life, while the control piglets were treated in the same way and time with physiological saline. The experimental and control groups were assigned to 6 age subgroups: 3, 14, 21, 35, 56 and 70 d of life. The animals from both groups were euthanised, then bone samples were collected and frozen at -25 degrees C until further analyses. Using dual-energy x-ray absorptiometry (DEXA method) bone mineral density of the femora was estimated. Additionally, 17-beta-oestradiol concentration in blood plasma was assayed using RIA-test. The obtained results indicate positive influence of enteral AKG administration on bone mineral density of the femur in piglets. Moreover, AKG increased the level of 17-beta-oestradiol in blood plasma in post-weaned piglets. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/222311
- author
- Kowalik, S ; Filip, RS ; Sliwa, E ; Tatara, MR ; Pierzynowski, Stefan LU and Studzinski, T
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 17-beta-oestradiol, bone mineral density, femur, piglets, alpha-ketoglutarate
- in
- Bulletin of the Veterinary Institute in Puławy
- volume
- 49
- issue
- 3
- pages
- 343 - 348
- publisher
- National Veterinary Research Institute
- external identifiers
-
- wos:000232255300017
- scopus:27644462120
- ISSN
- 0042-4870
- language
- English
- LU publication?
- yes
- id
- 6ba33ce4-2eed-421f-a9dd-6e2b356312f0 (old id 222311)
- alternative location
- http://www.piwet.pulawy.pl/doc/biuletyn_49-3/17_kowalik.pdf
- date added to LUP
- 2016-04-01 15:37:27
- date last changed
- 2022-01-28 06:16:33
@article{6ba33ce4-2eed-421f-a9dd-6e2b356312f0,
abstract = {{The aim of this study was to determine the influence of daily oral administration of alpha-ketoglutarate (AKG) on bone mineral density of the femur and concentration of 17-beta-oestradiol in blood plasma during 70 d of postnatal life in piglets. All the animals were kept under standard rearing conditions. AKG was administered orally from the 1(st) d of life, while the control piglets were treated in the same way and time with physiological saline. The experimental and control groups were assigned to 6 age subgroups: 3, 14, 21, 35, 56 and 70 d of life. The animals from both groups were euthanised, then bone samples were collected and frozen at -25 degrees C until further analyses. Using dual-energy x-ray absorptiometry (DEXA method) bone mineral density of the femora was estimated. Additionally, 17-beta-oestradiol concentration in blood plasma was assayed using RIA-test. The obtained results indicate positive influence of enteral AKG administration on bone mineral density of the femur in piglets. Moreover, AKG increased the level of 17-beta-oestradiol in blood plasma in post-weaned piglets.}},
author = {{Kowalik, S and Filip, RS and Sliwa, E and Tatara, MR and Pierzynowski, Stefan and Studzinski, T}},
issn = {{0042-4870}},
keywords = {{17-beta-oestradiol; bone mineral density; femur; piglets; alpha-ketoglutarate}},
language = {{eng}},
number = {{3}},
pages = {{343--348}},
publisher = {{National Veterinary Research Institute}},
series = {{Bulletin of the Veterinary Institute in Puławy}},
title = {{Influence of alpha-ketoglutarate on bone mineral density of the femur in piglets}},
url = {{http://www.piwet.pulawy.pl/doc/biuletyn_49-3/17_kowalik.pdf}},
volume = {{49}},
year = {{2005}},
}