Troponin T levels associated with genetic variants in NOTCH2 and MTNR1B in women with psychosis
(2017) In Psychiatry Research 250. p.217-220- Abstract
Psychosis patients have increased prevalence of metabolic disorders, which increase the risk for cardiovascular disease. Elevated troponin T level is an early biomarker of cardiovascular damage. We tested for association between troponin T levels and genetic risk variants of elevated blood glucose level in psychosis. Glucose and troponin T levels correlated positively. MTNR1B rs10830963 and NOTCH2 rs10923931 associated with troponin T levels in women, adjusted for glucose levels. These findings may indicate metabolic genetic influences on troponin T levels among women with psychosis.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/23ae7a89-a0a1-46a0-bdf3-c650e6ad428a
- author
- Hukic, Dzana Sudic ; Lavebratt, Catharina ; Olsson, Eric ; Östenson, Claes-Göran ; Eriksson, Sven V. ; Erlinge, David LU ; Schalling, Martin and Ösby, Urban
- organization
- publishing date
- 2017-04-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cardiovascular biomarker, Schizophrenia, Type 2 diabetes
- in
- Psychiatry Research
- volume
- 250
- pages
- 4 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:28167435
- wos:000397685200033
- scopus:85012305721
- ISSN
- 0165-1781
- DOI
- 10.1016/j.psychres.2017.01.030
- language
- English
- LU publication?
- yes
- id
- 23ae7a89-a0a1-46a0-bdf3-c650e6ad428a
- date added to LUP
- 2017-02-27 08:39:06
- date last changed
- 2024-10-14 01:22:53
@article{23ae7a89-a0a1-46a0-bdf3-c650e6ad428a, abstract = {{<p>Psychosis patients have increased prevalence of metabolic disorders, which increase the risk for cardiovascular disease. Elevated troponin T level is an early biomarker of cardiovascular damage. We tested for association between troponin T levels and genetic risk variants of elevated blood glucose level in psychosis. Glucose and troponin T levels correlated positively. MTNR1B rs10830963 and NOTCH2 rs10923931 associated with troponin T levels in women, adjusted for glucose levels. These findings may indicate metabolic genetic influences on troponin T levels among women with psychosis.</p>}}, author = {{Hukic, Dzana Sudic and Lavebratt, Catharina and Olsson, Eric and Östenson, Claes-Göran and Eriksson, Sven V. and Erlinge, David and Schalling, Martin and Ösby, Urban}}, issn = {{0165-1781}}, keywords = {{Cardiovascular biomarker; Schizophrenia; Type 2 diabetes}}, language = {{eng}}, month = {{04}}, pages = {{217--220}}, publisher = {{Elsevier}}, series = {{Psychiatry Research}}, title = {{Troponin T levels associated with genetic variants in NOTCH2 and MTNR1B in women with psychosis}}, url = {{http://dx.doi.org/10.1016/j.psychres.2017.01.030}}, doi = {{10.1016/j.psychres.2017.01.030}}, volume = {{250}}, year = {{2017}}, }