Effect of alpha-ketoglutarate given to pregnant sows on the development of the humerus and femur in newborns
(2005) In Bulletin of the Veterinary Institute in Puławy 49(1). p.117-120- Abstract
- Alpha-ketoglutarate (AKG) was given to pregnant sows every day starting from the 91(st) d of pregnancy to farrowing. At the same time control pregnant sows were treated in the same way with physiological saline (PhS). Newborn piglets from the experimental (AKG) and control (PhS) mothers were euthanised in 1 h after their birth, and the femora and humeri were isolated and frozen at -25 degrees C until further analyses. Using quantitative computed tomography (QCT) method, volumetric bone density of the cortical and trabecular bone compartments were estimated. Moreover, geometrical and mechanical parameters of the bones and the level of osteocalcin and alkaline phosphatase activity in serum were determined. It was found that the... (More)
- Alpha-ketoglutarate (AKG) was given to pregnant sows every day starting from the 91(st) d of pregnancy to farrowing. At the same time control pregnant sows were treated in the same way with physiological saline (PhS). Newborn piglets from the experimental (AKG) and control (PhS) mothers were euthanised in 1 h after their birth, and the femora and humeri were isolated and frozen at -25 degrees C until further analyses. Using quantitative computed tomography (QCT) method, volumetric bone density of the cortical and trabecular bone compartments were estimated. Moreover, geometrical and mechanical parameters of the bones and the level of osteocalcin and alkaline phosphatase activity in serum were determined. It was found that the administration of AKG to pregnant sows during 24 d before parturition decreased bone density in their newborns. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/246773
- author
- Sliwa, E ; Kowalik, S ; Tatara, MR ; Krupski, W ; Majcher, P ; Luszczewska-Sierakowska, I ; Pierzynowski, Stefan LU and Studzinski, T
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- alpha-ketoglutarate, piglets, sow, pregnancy, bone formation
- in
- Bulletin of the Veterinary Institute in Puławy
- volume
- 49
- issue
- 1
- pages
- 117 - 120
- publisher
- National Veterinary Research Institute
- external identifiers
-
- wos:000228098700023
- scopus:19344377948
- ISSN
- 0042-4870
- language
- English
- LU publication?
- yes
- id
- f98a451f-a4ab-469e-ad4c-defb1f78069e (old id 246773)
- alternative location
- http://www.piwet.pulawy.pl/doc/biuletyn_49-1/23_sliwa.pdf
- date added to LUP
- 2016-04-01 16:04:57
- date last changed
- 2022-01-28 17:11:42
@article{f98a451f-a4ab-469e-ad4c-defb1f78069e, abstract = {{Alpha-ketoglutarate (AKG) was given to pregnant sows every day starting from the 91(st) d of pregnancy to farrowing. At the same time control pregnant sows were treated in the same way with physiological saline (PhS). Newborn piglets from the experimental (AKG) and control (PhS) mothers were euthanised in 1 h after their birth, and the femora and humeri were isolated and frozen at -25 degrees C until further analyses. Using quantitative computed tomography (QCT) method, volumetric bone density of the cortical and trabecular bone compartments were estimated. Moreover, geometrical and mechanical parameters of the bones and the level of osteocalcin and alkaline phosphatase activity in serum were determined. It was found that the administration of AKG to pregnant sows during 24 d before parturition decreased bone density in their newborns.}}, author = {{Sliwa, E and Kowalik, S and Tatara, MR and Krupski, W and Majcher, P and Luszczewska-Sierakowska, I and Pierzynowski, Stefan and Studzinski, T}}, issn = {{0042-4870}}, keywords = {{alpha-ketoglutarate; piglets; sow; pregnancy; bone formation}}, language = {{eng}}, number = {{1}}, pages = {{117--120}}, publisher = {{National Veterinary Research Institute}}, series = {{Bulletin of the Veterinary Institute in Puławy}}, title = {{Effect of alpha-ketoglutarate given to pregnant sows on the development of the humerus and femur in newborns}}, url = {{http://www.piwet.pulawy.pl/doc/biuletyn_49-1/23_sliwa.pdf}}, volume = {{49}}, year = {{2005}}, }