Quality of Life and the Effect of Memantine in Dementia with Lewy Bodies and Parkinson's Disease Dementia.
(2011) In Dementia and Geriatric Cognitive Disorders 32(4). p.227-234- Abstract
- Aim: To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias. Methods: A secondary analysis of a randomized controlled study in 70 patients with Parkinson's disease dementia (PDD) or dementia with Lewy bodies (DLB) over 24 weeks using caregiver-rated QOL-Alzheimer's disease (AD) in domains according to the WHO's classification of health. Results: Baseline QOL shows lower ratings for body functions over environmental factors in DLB/PDD. Treatment with memantine significantly improves life as a whole compared to placebo and improves total QOL, body function and structure. Conclusion: This study shows that memantine improves QOL in Lewy body dementias. We also demonstrate important QOL... (More)
- Aim: To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias. Methods: A secondary analysis of a randomized controlled study in 70 patients with Parkinson's disease dementia (PDD) or dementia with Lewy bodies (DLB) over 24 weeks using caregiver-rated QOL-Alzheimer's disease (AD) in domains according to the WHO's classification of health. Results: Baseline QOL shows lower ratings for body functions over environmental factors in DLB/PDD. Treatment with memantine significantly improves life as a whole compared to placebo and improves total QOL, body function and structure. Conclusion: This study shows that memantine improves QOL in Lewy body dementias. We also demonstrate important QOL patterns which can be used in clinical practice. Copyright (C) 2011 S. Karger AG, Basel (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2494160
- author
- Larsson, Victoria LU ; Engedal, Knut ; Aarsland, Dag ; Wattmo, Carina LU ; Minthon, Lennart LU and Londos, Elisabet LU
- organization
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- quality of life, Dementia, Dementia with Lewy bodies, Parkinson's, Randomized controlled trial, disease dementia
- in
- Dementia and Geriatric Cognitive Disorders
- volume
- 32
- issue
- 4
- pages
- 227 - 234
- publisher
- Karger
- external identifiers
-
- wos:000300090700001
- scopus:82055175125
- pmid:22122992
- ISSN
- 1420-8008
- DOI
- 10.1159/000334523
- language
- English
- LU publication?
- yes
- id
- 7ccfb13a-99eb-469a-ac86-ada2434e876a (old id 2494160)
- date added to LUP
- 2016-04-01 11:02:48
- date last changed
- 2022-03-27 21:55:16
@article{7ccfb13a-99eb-469a-ac86-ada2434e876a, abstract = {{Aim: To investigate quality of life (QOL) and the effect of memantine treatment in patients with Lewy body dementias. Methods: A secondary analysis of a randomized controlled study in 70 patients with Parkinson's disease dementia (PDD) or dementia with Lewy bodies (DLB) over 24 weeks using caregiver-rated QOL-Alzheimer's disease (AD) in domains according to the WHO's classification of health. Results: Baseline QOL shows lower ratings for body functions over environmental factors in DLB/PDD. Treatment with memantine significantly improves life as a whole compared to placebo and improves total QOL, body function and structure. Conclusion: This study shows that memantine improves QOL in Lewy body dementias. We also demonstrate important QOL patterns which can be used in clinical practice. Copyright (C) 2011 S. Karger AG, Basel}}, author = {{Larsson, Victoria and Engedal, Knut and Aarsland, Dag and Wattmo, Carina and Minthon, Lennart and Londos, Elisabet}}, issn = {{1420-8008}}, keywords = {{quality of life; Dementia; Dementia with Lewy bodies; Parkinson's; Randomized controlled trial; disease dementia}}, language = {{eng}}, number = {{4}}, pages = {{227--234}}, publisher = {{Karger}}, series = {{Dementia and Geriatric Cognitive Disorders}}, title = {{Quality of Life and the Effect of Memantine in Dementia with Lewy Bodies and Parkinson's Disease Dementia.}}, url = {{http://dx.doi.org/10.1159/000334523}}, doi = {{10.1159/000334523}}, volume = {{32}}, year = {{2011}}, }