Memory aging and brain maintenance
(2012) In Trends in Cognitive Sciences 16(5). p.292-305- Abstract
- Episodic memory and working memory decline with advancing age. Nevertheless, large-scale population-based studies document well-preserved memory functioning in some older individuals. The influential 'reserve' notion holds that individual differences in brain characteristics or in the manner people process tasks allow some individuals to cope better than others with brain pathology and hence show preserved memory performance. Here, we discuss a complementary concept, that of brain maintenance (or relative lack of brain pathology), and argue that it constitutes the primary determinant of successful memory aging. We discuss evidence for brain maintenance at different levels: cellular, neurochemical, gray- and white-matter integrity, and... (More)
- Episodic memory and working memory decline with advancing age. Nevertheless, large-scale population-based studies document well-preserved memory functioning in some older individuals. The influential 'reserve' notion holds that individual differences in brain characteristics or in the manner people process tasks allow some individuals to cope better than others with brain pathology and hence show preserved memory performance. Here, we discuss a complementary concept, that of brain maintenance (or relative lack of brain pathology), and argue that it constitutes the primary determinant of successful memory aging. We discuss evidence for brain maintenance at different levels: cellular, neurochemical, gray- and white-matter integrity, and systems-level activation patterns. Various genetic and lifestyle factors support brain maintenance in aging and interventions may be designed to promote maintenance of brain structure and function in late life. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2826798
- author
- Nyberg, Lars ; Lövdén, Martin LU ; Riklund, Katrine ; Lindenberger, Ulman and Backman, Lars
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Trends in Cognitive Sciences
- volume
- 16
- issue
- 5
- pages
- 292 - 305
- publisher
- Elsevier
- external identifiers
-
- wos:000304026200010
- scopus:84860379706
- ISSN
- 1364-6613
- DOI
- 10.1016/j.tics.2012.04.005
- language
- English
- LU publication?
- yes
- id
- fd4c93d3-d9c5-4a10-a2b6-01de00ac4c37 (old id 2826798)
- date added to LUP
- 2016-04-01 10:12:00
- date last changed
- 2022-04-27 19:10:12
@article{fd4c93d3-d9c5-4a10-a2b6-01de00ac4c37,
abstract = {{Episodic memory and working memory decline with advancing age. Nevertheless, large-scale population-based studies document well-preserved memory functioning in some older individuals. The influential 'reserve' notion holds that individual differences in brain characteristics or in the manner people process tasks allow some individuals to cope better than others with brain pathology and hence show preserved memory performance. Here, we discuss a complementary concept, that of brain maintenance (or relative lack of brain pathology), and argue that it constitutes the primary determinant of successful memory aging. We discuss evidence for brain maintenance at different levels: cellular, neurochemical, gray- and white-matter integrity, and systems-level activation patterns. Various genetic and lifestyle factors support brain maintenance in aging and interventions may be designed to promote maintenance of brain structure and function in late life.}},
author = {{Nyberg, Lars and Lövdén, Martin and Riklund, Katrine and Lindenberger, Ulman and Backman, Lars}},
issn = {{1364-6613}},
language = {{eng}},
number = {{5}},
pages = {{292--305}},
publisher = {{Elsevier}},
series = {{Trends in Cognitive Sciences}},
title = {{Memory aging and brain maintenance}},
url = {{http://dx.doi.org/10.1016/j.tics.2012.04.005}},
doi = {{10.1016/j.tics.2012.04.005}},
volume = {{16}},
year = {{2012}},
}