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New directions of miniaturization within the proteomics research area

Marko-Varga, György LU ; Nilsson, Johan LU and Laurell, Thomas LU (2003) In Electrophoresis 24(21). p.3521-3532
Abstract
An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
proteomics, miniaturization, protein expression profiling, review
in
Electrophoresis
volume
24
issue
21
pages
3521 - 3532
publisher
John Wiley & Sons Inc.
external identifiers
  • wos:000186858700002
  • pmid:14613179
  • scopus:0347764579
ISSN
0173-0835
DOI
10.1002/elps.200305666
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biomedical Engineering (011200011), Analytical Chemistry (S/LTH) (011001004)
id
ced33133-61e6-4a21-85dd-dd8475cb61f5 (old id 294619)
date added to LUP
2016-04-01 12:29:51
date last changed
2022-01-27 05:54:12
@article{ced33133-61e6-4a21-85dd-dd8475cb61f5,
  abstract     = {{An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.}},
  author       = {{Marko-Varga, György and Nilsson, Johan and Laurell, Thomas}},
  issn         = {{0173-0835}},
  keywords     = {{proteomics; miniaturization; protein expression profiling; review}},
  language     = {{eng}},
  number       = {{21}},
  pages        = {{3521--3532}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Electrophoresis}},
  title        = {{New directions of miniaturization within the proteomics research area}},
  url          = {{http://dx.doi.org/10.1002/elps.200305666}},
  doi          = {{10.1002/elps.200305666}},
  volume       = {{24}},
  year         = {{2003}},
}