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An automated method for the detection of pulmonary embolism in V/Q-scans

Frigyesi, Attila LU (2003) In Medical Image Analysis 7(3). p.341-349
Abstract
In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused areas are used as features. With the aid of these features a simple test for PE is devised. The method is evaluated on two sets of patients. One set comprises 102 patients who have undergone both V/Q-scanning and angiography. The performance given as the area under the Receiver Operating Characteristic (ROC) curve is 0.85. Another set is made up by... (More)
In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused areas are used as features. With the aid of these features a simple test for PE is devised. The method is evaluated on two sets of patients. One set comprises 102 patients who have undergone both V/Q-scanning and angiography. The performance given as the area under the Receiver Operating Characteristic (ROC) curve is 0.85. Another set is made up by the 507 consecutive patients examined with V/Q-scanning at Lund University Hospital in Sweden. In this case, the reference was the consensus opinion of two radiologists, the ROC-area is 0.67. A fully automatic and reasonably robust expert system is developed to aid the radiologist in the interpretation of V/Q-scans for PE. (C) 2003 Elsevier B.V. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
automated method, pulmonary embolism, V/Q-scans
in
Medical Image Analysis
volume
7
issue
3
pages
341 - 349
publisher
Elsevier
external identifiers
  • pmid:12946472
  • wos:000185435300009
  • scopus:0042827521
ISSN
1361-8415
DOI
10.1016/S1361-8415(03)00030-6
language
English
LU publication?
yes
id
25545245-9559-4430-a4dd-09f7395c1cbc (old id 300041)
date added to LUP
2016-04-01 12:08:30
date last changed
2022-02-03 18:06:46
@article{25545245-9559-4430-a4dd-09f7395c1cbc,
  abstract     = {{In this paper, a fully automatic method for the diagnosis of pulmonary embolism (PE) from V/Q-scans is presented. Image analysis is applied to the ventilation and the perfusion images obtained in the V/Q-scan. The difference of the ventilation and the perfusion is calculated after transformation and hot-spot reduction of the images. From this difference image the integral of the underperfused areas are used as features. With the aid of these features a simple test for PE is devised. The method is evaluated on two sets of patients. One set comprises 102 patients who have undergone both V/Q-scanning and angiography. The performance given as the area under the Receiver Operating Characteristic (ROC) curve is 0.85. Another set is made up by the 507 consecutive patients examined with V/Q-scanning at Lund University Hospital in Sweden. In this case, the reference was the consensus opinion of two radiologists, the ROC-area is 0.67. A fully automatic and reasonably robust expert system is developed to aid the radiologist in the interpretation of V/Q-scans for PE. (C) 2003 Elsevier B.V. All rights reserved.}},
  author       = {{Frigyesi, Attila}},
  issn         = {{1361-8415}},
  keywords     = {{automated method; pulmonary embolism; V/Q-scans}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{341--349}},
  publisher    = {{Elsevier}},
  series       = {{Medical Image Analysis}},
  title        = {{An automated method for the detection of pulmonary embolism in V/Q-scans}},
  url          = {{http://dx.doi.org/10.1016/S1361-8415(03)00030-6}},
  doi          = {{10.1016/S1361-8415(03)00030-6}},
  volume       = {{7}},
  year         = {{2003}},
}