Dacrymenone and VM 3298-2 - New antibiotics with antibacterial and antifungal activity
(2003) In Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences 58(7-8). p.541-546- Abstract
- Two new antibiotic metabolites, dacrymenone (1) and VM 3298-2 (2), were isolated from fermentations of a Dacrymyces sp., and their structures were determined by spectroscopic techniques. Dacrymenone (1) is a new eremophilane sesquiterpenoid while VM 3298-2 (2) is a bis-enol ether between methyl pyruvate and 4,6-dihydroxycyclohexan-1,3-dione. Dacrymenone (1) shows weak antibacterial and antifungal activity while VM 3298-2 (2) exhibits cytotoxic and antifungal activities.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/301538
- author
- Mierau, V ; Anke, T and Sterner, Olov LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- antifungal antibiotic, eremophilanes, Dacrymyces
- in
- Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
- volume
- 58
- issue
- 7-8
- pages
- 541 - 546
- publisher
- Verlag der Zeitschrift für Naturforschung
- external identifiers
-
- wos:000185144500016
- scopus:0041655935
- ISSN
- 0939-5075
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
- id
- 79c8a573-b467-41d7-8e67-9391fad9747e (old id 301538)
- alternative location
- http://www.znaturforsch.com/ac/v58c/s58c0541.pdf
- date added to LUP
- 2016-04-01 16:07:53
- date last changed
- 2022-01-28 17:28:15
@article{79c8a573-b467-41d7-8e67-9391fad9747e, abstract = {{Two new antibiotic metabolites, dacrymenone (1) and VM 3298-2 (2), were isolated from fermentations of a Dacrymyces sp., and their structures were determined by spectroscopic techniques. Dacrymenone (1) is a new eremophilane sesquiterpenoid while VM 3298-2 (2) is a bis-enol ether between methyl pyruvate and 4,6-dihydroxycyclohexan-1,3-dione. Dacrymenone (1) shows weak antibacterial and antifungal activity while VM 3298-2 (2) exhibits cytotoxic and antifungal activities.}}, author = {{Mierau, V and Anke, T and Sterner, Olov}}, issn = {{0939-5075}}, keywords = {{antifungal antibiotic; eremophilanes; Dacrymyces}}, language = {{eng}}, number = {{7-8}}, pages = {{541--546}}, publisher = {{Verlag der Zeitschrift für Naturforschung}}, series = {{Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences}}, title = {{Dacrymenone and VM 3298-2 - New antibiotics with antibacterial and antifungal activity}}, url = {{http://www.znaturforsch.com/ac/v58c/s58c0541.pdf}}, volume = {{58}}, year = {{2003}}, }