A hypothesis about tumour development and the clinical features of hereditary breast cancers
(2001) In European Journal of Cancer 37(16). p.2023-2029- Abstract
A unifying hypothesis is presented about tumour biology in hereditary breast cancer in relation to the epithelial origin and the degree of differentiation of the normal epithelium at the time of tumour initiation. By using different breast cancer syndromes as examples, it is possible to, at least partly, predict the tumour biology, clinical presentation and therapeutic response.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/306100e1-cdff-472c-b336-3b3ad4eb66ce
- author
- Olsson, H LU
- publishing date
- 2001-11
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adult, Ataxia Telangiectasia Mutated Proteins, Breast Neoplasms, Cell Cycle Proteins, Cell Transformation, Neoplastic, DNA-Binding Proteins, Female, Genes, BRCA1, Genes, BRCA2, Genes, p53, Humans, Middle Aged, Mutation, Neoplasm Proteins, Neoplastic Syndromes, Hereditary, Protein-Serine-Threonine Kinases, Tumor Suppressor Proteins
- in
- European Journal of Cancer
- volume
- 37
- issue
- 16
- pages
- 2023 - 2029
- publisher
- Elsevier
- external identifiers
-
- scopus:0034774288
- pmid:11597380
- ISSN
- 0959-8049
- DOI
- 10.1016/S0959-8049(01)00228-3
- language
- English
- LU publication?
- no
- id
- 306100e1-cdff-472c-b336-3b3ad4eb66ce
- date added to LUP
- 2016-09-18 12:23:09
- date last changed
- 2024-01-04 12:28:09
@article{306100e1-cdff-472c-b336-3b3ad4eb66ce, abstract = {{<p>A unifying hypothesis is presented about tumour biology in hereditary breast cancer in relation to the epithelial origin and the degree of differentiation of the normal epithelium at the time of tumour initiation. By using different breast cancer syndromes as examples, it is possible to, at least partly, predict the tumour biology, clinical presentation and therapeutic response.</p>}}, author = {{Olsson, H}}, issn = {{0959-8049}}, keywords = {{Adult; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Cell Cycle Proteins; Cell Transformation, Neoplastic; DNA-Binding Proteins; Female; Genes, BRCA1; Genes, BRCA2; Genes, p53; Humans; Middle Aged; Mutation; Neoplasm Proteins; Neoplastic Syndromes, Hereditary; Protein-Serine-Threonine Kinases; Tumor Suppressor Proteins}}, language = {{eng}}, number = {{16}}, pages = {{2023--2029}}, publisher = {{Elsevier}}, series = {{European Journal of Cancer}}, title = {{A hypothesis about tumour development and the clinical features of hereditary breast cancers}}, url = {{http://dx.doi.org/10.1016/S0959-8049(01)00228-3}}, doi = {{10.1016/S0959-8049(01)00228-3}}, volume = {{37}}, year = {{2001}}, }