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Single Photon Emission Computed Tomography (SPECT) and SPECT/CT Hybrid Imaging

Ljungberg, Michael LU and Erlandsson, Kjell (2022) In Series in Medical Physics and Biomedical Engineering 1.
Abstract
Images created using a standard collimator-based scintillation camera are essentially 2D images, lacking information regarding the source depth, since the value in a particular pixel in the image represents detection of photons along a line determined by the collimator. However, it is possible to reconstruct a set of 2D images that together form a 3D image of the underlying activity distribution from data acquired of the same source distribution at different projection angles around the object. This chapter will describe the way in which these data can be used to reconstruct transversal images by the filtered back-projection (FBP) method as well as by iterative algorithms, and also how noise regularization can be implemented. Various... (More)
Images created using a standard collimator-based scintillation camera are essentially 2D images, lacking information regarding the source depth, since the value in a particular pixel in the image represents detection of photons along a line determined by the collimator. However, it is possible to reconstruct a set of 2D images that together form a 3D image of the underlying activity distribution from data acquired of the same source distribution at different projection angles around the object. This chapter will describe the way in which these data can be used to reconstruct transversal images by the filtered back-projection (FBP) method as well as by iterative algorithms, and also how noise regularization can be implemented. Various physical factors that affect the reconstructed images will also be discussed. If we combine a SPECT system with a CT system and display the images from both as a single hybrid image, additional useful information can be obtained. The CT information can also be used to correct for non-homogeneous attenuation, scatter, and partial-volume effects. Finally, the chapter will discuss how the combination of quantitative SPECT images registered to CT images can be used for dosimetry calculations. (Less)
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures - Instrumentation and Imaging Procedures
series title
Series in Medical Physics and Biomedical Engineering
editor
Ljungberg, Michael
volume
1
edition
1
pages
17 pages
publisher
CRC Press
ISBN
9780429489556
9781138593268
language
English
LU publication?
yes
id
30f5b603-02a5-406d-8fb2-9e4cbeba895c
alternative location
https://www.taylorfrancis.com/chapters/edit/10.1201/9780429489556-16/single-photon-emission-computed-tomography-spect-spect-ct-hybrid-imaging-michael-ljungberg-kjell-erlandsson?context=ubx&refId=5f491053-5706-480e-af96-e32883902ce6
date added to LUP
2023-05-26 10:55:28
date last changed
2023-05-26 10:55:28
@inbook{30f5b603-02a5-406d-8fb2-9e4cbeba895c,
  abstract     = {{Images created using a standard collimator-based scintillation camera are essentially 2D images, lacking information regarding the source depth, since the value in a particular pixel in the image represents detection of photons along a line determined by the collimator. However, it is possible to reconstruct a set of 2D images that together form a 3D image of the underlying activity distribution from data acquired of the same source distribution at different projection angles around the object. This chapter will describe the way in which these data can be used to reconstruct transversal images by the filtered back-projection (FBP) method as well as by iterative algorithms, and also how noise regularization can be implemented. Various physical factors that affect the reconstructed images will also be discussed. If we combine a SPECT system with a CT system and display the images from both as a single hybrid image, additional useful information can be obtained. The CT information can also be used to correct for non-homogeneous attenuation, scatter, and partial-volume effects. Finally, the chapter will discuss how the combination of quantitative SPECT images registered to CT images can be used for dosimetry calculations.}},
  author       = {{Ljungberg, Michael and Erlandsson, Kjell}},
  booktitle    = {{Handbook of Nuclear Medicine and Molecular Imaging for Physicists : Instrumentation and Imaging Procedures}},
  editor       = {{Ljungberg, Michael}},
  isbn         = {{9780429489556}},
  language     = {{eng}},
  month        = {{04}},
  publisher    = {{CRC Press}},
  series       = {{Series in Medical Physics and Biomedical Engineering}},
  title        = {{Single Photon Emission Computed Tomography (SPECT) and SPECT/CT Hybrid Imaging}},
  url          = {{https://www.taylorfrancis.com/chapters/edit/10.1201/9780429489556-16/single-photon-emission-computed-tomography-spect-spect-ct-hybrid-imaging-michael-ljungberg-kjell-erlandsson?context=ubx&refId=5f491053-5706-480e-af96-e32883902ce6}},
  volume       = {{1}},
  year         = {{2022}},
}