Inflammatory markers and mortality in critical lower limb ischemia
(2013) p.91-96- Abstract
In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes in endothelial cells [1, 2]. Important cytokines are, for example, tumor necrosis factor a [3], neopterin [4], and interleukin-6 [3, 5]. Expression of the immune mediator CD40 ligand is increased in atherogenesis [6, 7], and prostaglandin-like isoprostanes [8, 9] are markers of lipid peroxidation and believed to contribute to atherosclerosis... (More)
In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes in endothelial cells [1, 2]. Important cytokines are, for example, tumor necrosis factor a [3], neopterin [4], and interleukin-6 [3, 5]. Expression of the immune mediator CD40 ligand is increased in atherogenesis [6, 7], and prostaglandin-like isoprostanes [8, 9] are markers of lipid peroxidation and believed to contribute to atherosclerosis and thrombosis [10].
(Less)
- author
- Gottsäter, Anders LU
- organization
- publishing date
- 2013-01-01
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Inflammatory Response in Cardiovascular Surgery
- editor
- Gabriel, Edmo A. and Gabriel, Sthefano A.
- pages
- 6 pages
- publisher
- Springer
- external identifiers
-
- scopus:84956521154
- ISBN
- 9781447144281
- 9781447144298
- language
- English
- LU publication?
- yes
- id
- 377dd36f-de06-45f0-add8-0001821eebc8
- alternative location
- https://link.springer.com/chapter/10.1007/978-1-4471-4429-8_13
- date added to LUP
- 2020-12-11 14:08:58
- date last changed
- 2024-08-22 10:34:34
@inbook{377dd36f-de06-45f0-add8-0001821eebc8, abstract = {{<p>In atherosclerotic vascular disease, endothelial dysfunction is induced by risk factors such as arterial hypertension, hypercholesterolemia, and tobacco use. In fl ammatory mechanisms and in fl ammatory cytokines play important roles in all of these mechanisms, and the different steps in atherogenesis involve cytokines as in fl ammatory promoters, stimulating the expression of proatherogenic genes in endothelial cells [1, 2]. Important cytokines are, for example, tumor necrosis factor a [3], neopterin [4], and interleukin-6 [3, 5]. Expression of the immune mediator CD40 ligand is increased in atherogenesis [6, 7], and prostaglandin-like isoprostanes [8, 9] are markers of lipid peroxidation and believed to contribute to atherosclerosis and thrombosis [10].</p>}}, author = {{Gottsäter, Anders}}, booktitle = {{Inflammatory Response in Cardiovascular Surgery}}, editor = {{Gabriel, Edmo A. and Gabriel, Sthefano A.}}, isbn = {{9781447144281}}, language = {{eng}}, month = {{01}}, pages = {{91--96}}, publisher = {{Springer}}, title = {{Inflammatory markers and mortality in critical lower limb ischemia}}, url = {{https://link.springer.com/chapter/10.1007/978-1-4471-4429-8_13}}, year = {{2013}}, }