MLL/GAS7 fusion in a pediatric case of t(11;17)(q23;p13)-positive precursor B-cell acute lymphoblastic leukemia
Panagopoulos, Ioannis LU ; Lilljebjörn, Henrik LU
; Strömbeck, Bodil
LU
; Hjorth, Lars
LU
; Olofsson, Tor
LU
and Johansson, Bertil
LU
(2006)
In Haematologica
91(9).
p.1287-1288
- Abstract
- AML/GAS7, resulting from t(11;17)(q23;p13), has been reported in one case of treatment-related acute myeloid leukemia (AML). We present a de novo case of t(11;17)-positive pediatric acute lymphoblastic leukemia. Fluorescent in situ hybridization and reverse transcriptase polymerase chain reaction analyses revealed an MLL/GAS7 chimera identical to the one previously described in AML. The molecular genetic features of MLL/GAS7 and the clinical impact of t(11;17) are discussed.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/394180
- author
- Panagopoulos, Ioannis
LU
; Lilljebjörn, Henrik
LU
; Strömbeck, Bodil
LU
; Hjorth, Lars
LU
; Olofsson, Tor
LU
and Johansson, Bertil
LU
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- GAS7, MLL, ALL, translocation, fusion
- in
- Haematologica
- volume
- 91
- issue
- 9
- pages
- 1287 - 1288
- publisher
- Ferrata Storti Foundation
- external identifiers
-
- wos:000240353100028
- pmid:16956839
- scopus:33748782773
- ISSN
- 1592-8721
- language
- English
- LU publication?
- yes
- id
- 03de4f16-4961-4d57-bb67-216411318133 (old id 394180)
- alternative location
- http://www.haematologica.org/cgi/content/abstract/91/9/1287
- date added to LUP
- 2016-04-01 16:14:11
- date last changed
- 2022-01-28 18:17:37
@article{03de4f16-4961-4d57-bb67-216411318133,
abstract = {{AML/GAS7, resulting from t(11;17)(q23;p13), has been reported in one case of treatment-related acute myeloid leukemia (AML). We present a de novo case of t(11;17)-positive pediatric acute lymphoblastic leukemia. Fluorescent in situ hybridization and reverse transcriptase polymerase chain reaction analyses revealed an MLL/GAS7 chimera identical to the one previously described in AML. The molecular genetic features of MLL/GAS7 and the clinical impact of t(11;17) are discussed.}},
author = {{Panagopoulos, Ioannis and Lilljebjörn, Henrik and Strömbeck, Bodil and Hjorth, Lars and Olofsson, Tor and Johansson, Bertil}},
issn = {{1592-8721}},
keywords = {{GAS7; MLL; ALL; translocation; fusion}},
language = {{eng}},
number = {{9}},
pages = {{1287--1288}},
publisher = {{Ferrata Storti Foundation}},
series = {{Haematologica}},
title = {{MLL/GAS7 fusion in a pediatric case of t(11;17)(q23;p13)-positive precursor B-cell acute lymphoblastic leukemia}},
url = {{http://www.haematologica.org/cgi/content/abstract/91/9/1287}},
volume = {{91}},
year = {{2006}},
}