Identification of transcriptional subgroups in EGFR-mutated and EGFR/KRAS-wild type lung adenocarcinoma reveals gene signatures associated with patient outcome.
Planck, Maria LU ; Isaksson, Sofi LU ; Veerla, Srinivas LU
and Staaf, Johan
LU
(2013)
In Clinical Cancer Research
19(18).
p.5116-5126
- Abstract
- In lung adenocarcinoma, EGFR and KRAS mutations dominate the mutational spectrum and have clear therapeutic implications. We sought to determine whether transcriptional subgroups of clinical relevance exist within EGFR-mutated, KRAS-mutated, or EGFR and KRAS-wild type (EGFRwt/KRASwt) adenocarcinomas.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4005818
- author
- Planck, Maria
LU
; Isaksson, Sofi
LU
; Veerla, Srinivas
LU
and Staaf, Johan
LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Clinical Cancer Research
- volume
- 19
- issue
- 18
- pages
- 5116 - 5126
- publisher
- American Association for Cancer Research Inc.
- external identifiers
-
- wos:000324513000022
- pmid:23938291
- scopus:84884567019
- pmid:23938291
- ISSN
- 1078-0432
- DOI
- 10.1158/1078-0432.CCR-13-0928
- language
- English
- LU publication?
- yes
- id
- 6f4c2210-c3fe-4ad5-b581-f07f81bea5cf (old id 4005818)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23938291?dopt=Abstract
- date added to LUP
- 2016-04-01 10:32:40
- date last changed
- 2025-10-14 10:40:35
@article{6f4c2210-c3fe-4ad5-b581-f07f81bea5cf,
abstract = {{In lung adenocarcinoma, EGFR and KRAS mutations dominate the mutational spectrum and have clear therapeutic implications. We sought to determine whether transcriptional subgroups of clinical relevance exist within EGFR-mutated, KRAS-mutated, or EGFR and KRAS-wild type (EGFRwt/KRASwt) adenocarcinomas.}},
author = {{Planck, Maria and Isaksson, Sofi and Veerla, Srinivas and Staaf, Johan}},
issn = {{1078-0432}},
language = {{eng}},
number = {{18}},
pages = {{5116--5126}},
publisher = {{American Association for Cancer Research Inc.}},
series = {{Clinical Cancer Research}},
title = {{Identification of transcriptional subgroups in EGFR-mutated and EGFR/KRAS-wild type lung adenocarcinoma reveals gene signatures associated with patient outcome.}},
url = {{http://dx.doi.org/10.1158/1078-0432.CCR-13-0928}},
doi = {{10.1158/1078-0432.CCR-13-0928}},
volume = {{19}},
year = {{2013}},
}