Visibility of single spiculations in digital breast tomosynthesis
(2013) SPIE Medical Imaging, 2013 8673. p.86731-86731- Abstract
- Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plane parallel to the detector. They were assumed to consist of a fibroglandular tissue composition. The length of the spiculations was 5 mm while the diameter varied (0.12 - 0.28 mm). Reconstructed central slices of the lesion, separated by insertion in fatty or dense breasts (100 images in each), were used in 4-alternative forced choice (4AFC) human... (More)
- Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plane parallel to the detector. They were assumed to consist of a fibroglandular tissue composition. The length of the spiculations was 5 mm while the diameter varied (0.12 - 0.28 mm). Reconstructed central slices of the lesion, separated by insertion in fatty or dense breasts (100 images in each), were used in 4-alternative forced choice (4AFC) human observer experiments. Three different reconstructions were used: filtered back projection (FBP) with 1 mm thick slices and a statistical artifact reduction reconstruction (SAR) method generating 1 and 2 mm thick slices. Five readers participated and their task was to locate the spiculation in randomly presented images from the whole image set (4 diameters x 100 images). The percent correct (PC) decision was determined in both fat and dense tissue for all spiculation diameters and reconstructions. Results: At a PC level of 95% the required diameter was about 0.17 - 0.22 mm in dense tissue, and 0.18 - 0.26 mm in fatty tissue (depending upon reconstruction). Conclusions: SAR was found to be a promising alternative to FBP. The visibility of single spiculations was determined. The required diameter depends on both tissue composition and reconstruction. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4027042
- author
- Timberg, Pontus LU ; Dustler, Magnus LU ; Förnvik, Daniel LU and Zackrisson, Sophia LU
- organization
- publishing date
- 2013
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Breast Tomosynthesis, Lesion simulation, Spiculation, 4AFC, Reconstruction methods
- host publication
- Medical Imaging 2013: Image Perception, Observer Performance, And Technology Assessment
- volume
- 8673
- pages
- 86731 - 86731
- publisher
- SPIE
- conference name
- SPIE Medical Imaging, 2013
- conference location
- Lake Buena Vista (Orlando area), Florida, United States
- conference dates
- 2013-02-09 - 2013-02-14
- external identifiers
-
- wos:000322986700045
- scopus:84878800813
- ISSN
- 1996-756X
- 0277-786X
- DOI
- 10.1117/12.2005853
- language
- English
- LU publication?
- yes
- id
- 187cd137-eeae-4b86-98e8-8fc2dc1588d7 (old id 4027042)
- date added to LUP
- 2016-04-01 10:29:16
- date last changed
- 2024-08-11 23:22:04
@inproceedings{187cd137-eeae-4b86-98e8-8fc2dc1588d7, abstract = {{Purpose: To investigate the visibility of single spiculations in digital breast tomosynthesis (DBT). Method: Simulated spheres (6 mm diameter) with single spiculations were added to projection images acquired on a DBT system (MAMMOMAT Inspiration, Siemens). The spiculations had a cylindrical shape and were randomly, diagonally aligned (at four different positions: +/- pi/4 or +/- 3 pi/4) at a plane parallel to the detector. They were assumed to consist of a fibroglandular tissue composition. The length of the spiculations was 5 mm while the diameter varied (0.12 - 0.28 mm). Reconstructed central slices of the lesion, separated by insertion in fatty or dense breasts (100 images in each), were used in 4-alternative forced choice (4AFC) human observer experiments. Three different reconstructions were used: filtered back projection (FBP) with 1 mm thick slices and a statistical artifact reduction reconstruction (SAR) method generating 1 and 2 mm thick slices. Five readers participated and their task was to locate the spiculation in randomly presented images from the whole image set (4 diameters x 100 images). The percent correct (PC) decision was determined in both fat and dense tissue for all spiculation diameters and reconstructions. Results: At a PC level of 95% the required diameter was about 0.17 - 0.22 mm in dense tissue, and 0.18 - 0.26 mm in fatty tissue (depending upon reconstruction). Conclusions: SAR was found to be a promising alternative to FBP. The visibility of single spiculations was determined. The required diameter depends on both tissue composition and reconstruction.}}, author = {{Timberg, Pontus and Dustler, Magnus and Förnvik, Daniel and Zackrisson, Sophia}}, booktitle = {{Medical Imaging 2013: Image Perception, Observer Performance, And Technology Assessment}}, issn = {{1996-756X}}, keywords = {{Breast Tomosynthesis; Lesion simulation; Spiculation; 4AFC; Reconstruction methods}}, language = {{eng}}, pages = {{86731--86731}}, publisher = {{SPIE}}, title = {{Visibility of single spiculations in digital breast tomosynthesis}}, url = {{http://dx.doi.org/10.1117/12.2005853}}, doi = {{10.1117/12.2005853}}, volume = {{8673}}, year = {{2013}}, }