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Evaluation of breathing interplay effects during VMAT by using 3D gel measurements

Ceberg, Sofie LU ; Ceberg, Crister LU orcid ; Falk, M. ; af Rosenschold, P. Munk and Bäck, Sven LU (2013) 7th International Conference on 3D Radiation Dosimetry (IC3DDose) 444. p.012098-012098
Abstract
Respiratory motion during dynamic radiotherapy may affect the absorbed dose distribution both by dose-reducing smoothing and by more complicated interplay effects. In this study we present a novel method to determine the relative importance of these two effects. For the two dynamic deliveries studied in this work, the expected target dose reduction due to the smoothing effect was estimated by measurements convolved by the motion function. Remaining absorbed dose differences were attributed to interplay effects between the motion of the gel phantom and the movement of the modulating MLC leaves during modulated arc radiotherapy. The total dosimetric effect due to breathing motion and dynamic MLC motion during VMAT delivery resulted in an... (More)
Respiratory motion during dynamic radiotherapy may affect the absorbed dose distribution both by dose-reducing smoothing and by more complicated interplay effects. In this study we present a novel method to determine the relative importance of these two effects. For the two dynamic deliveries studied in this work, the expected target dose reduction due to the smoothing effect was estimated by measurements convolved by the motion function. Remaining absorbed dose differences were attributed to interplay effects between the motion of the gel phantom and the movement of the modulating MLC leaves during modulated arc radiotherapy. The total dosimetric effect due to breathing motion and dynamic MLC motion during VMAT delivery resulted in an average of about 4% target dose reduction. Comparing with only the smoothing effect, the average difference was decreased to around 1%, and the remaining distribution was attributed to interplay effects. Although the interplay effects were small compared to the smoothing effect, the standard deviations of 1.4-2.3% (1SD) were larger than the narrow distribution for repeated stationary measurement with a standard deviation between 0.5-0.9% (1SD). (Less)
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author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
7th International Conference on 3D Radiation Dosimetry (IC3DDose)
volume
444
pages
012098 - 012098
publisher
IOP Publishing
conference name
7th International Conference on 3D Radiation Dosimetry (IC3DDose)
conference location
Sydney, Australia
conference dates
2012-11-04 - 2012-11-08
external identifiers
  • wos:000322968600098
  • scopus:84883401595
ISSN
1742-6596
1742-6588
DOI
10.1088/1742-6596/444/1/012098
language
English
LU publication?
yes
id
51ae4453-7e2b-40d1-b589-79cc9dd5809e (old id 4027071)
date added to LUP
2016-04-01 10:39:15
date last changed
2024-04-21 17:28:17
@inproceedings{51ae4453-7e2b-40d1-b589-79cc9dd5809e,
  abstract     = {{Respiratory motion during dynamic radiotherapy may affect the absorbed dose distribution both by dose-reducing smoothing and by more complicated interplay effects. In this study we present a novel method to determine the relative importance of these two effects. For the two dynamic deliveries studied in this work, the expected target dose reduction due to the smoothing effect was estimated by measurements convolved by the motion function. Remaining absorbed dose differences were attributed to interplay effects between the motion of the gel phantom and the movement of the modulating MLC leaves during modulated arc radiotherapy. The total dosimetric effect due to breathing motion and dynamic MLC motion during VMAT delivery resulted in an average of about 4% target dose reduction. Comparing with only the smoothing effect, the average difference was decreased to around 1%, and the remaining distribution was attributed to interplay effects. Although the interplay effects were small compared to the smoothing effect, the standard deviations of 1.4-2.3% (1SD) were larger than the narrow distribution for repeated stationary measurement with a standard deviation between 0.5-0.9% (1SD).}},
  author       = {{Ceberg, Sofie and Ceberg, Crister and Falk, M. and af Rosenschold, P. Munk and Bäck, Sven}},
  booktitle    = {{7th International Conference on 3D Radiation Dosimetry (IC3DDose)}},
  issn         = {{1742-6596}},
  language     = {{eng}},
  pages        = {{012098--012098}},
  publisher    = {{IOP Publishing}},
  title        = {{Evaluation of breathing interplay effects during VMAT by using 3D gel measurements}},
  url          = {{http://dx.doi.org/10.1088/1742-6596/444/1/012098}},
  doi          = {{10.1088/1742-6596/444/1/012098}},
  volume       = {{444}},
  year         = {{2013}},
}