Determination of the biodistribution and dosimetry of (123)I-FP-CIT in male patients with suspected Parkinsonism or Lewy body dementia using planar and combined planar and SPECT/CT imaging.
(2013) In Applied Radiation and Isotopes 82. p.300-307- Abstract
- In this study, (123)I-FP-CIT biodistribution and dosimetry was determined in 10 adult male patients using planar gamma camera imaging alone or in combination with single photon emission computed tomography /X-ray computed tomography (SPECT/CT) imaging. Dosimetric assessment using planar plus SPECT/CT imaging resulted in significantly different estimates of organ-absorbed doses compared to estimates based on planar imaging alone. We conclude that the use of complementary SPECT/CT measurements in biodistribution studies is valuable for determining the organ doses more accurately.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4143196
- author
- Sydoff, Marie LU ; Lizana, Helena ; Mattsson, Sören LU ; Stabin, Michael G and Leide Svegborn, Sigrid LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Radiation and Isotopes
- volume
- 82
- pages
- 300 - 307
- publisher
- Elsevier
- external identifiers
-
- wos:000328804000046
- pmid:24135637
- scopus:84885929322
- ISSN
- 0969-8043
- DOI
- 10.1016/j.apradiso.2013.09.006
- language
- English
- LU publication?
- yes
- id
- 2607169e-8388-4453-a096-a0a21ea839a6 (old id 4143196)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24135637?dopt=Abstract
- date added to LUP
- 2016-04-01 10:50:25
- date last changed
- 2022-01-26 02:55:25
@article{2607169e-8388-4453-a096-a0a21ea839a6, abstract = {{In this study, (123)I-FP-CIT biodistribution and dosimetry was determined in 10 adult male patients using planar gamma camera imaging alone or in combination with single photon emission computed tomography /X-ray computed tomography (SPECT/CT) imaging. Dosimetric assessment using planar plus SPECT/CT imaging resulted in significantly different estimates of organ-absorbed doses compared to estimates based on planar imaging alone. We conclude that the use of complementary SPECT/CT measurements in biodistribution studies is valuable for determining the organ doses more accurately.}}, author = {{Sydoff, Marie and Lizana, Helena and Mattsson, Sören and Stabin, Michael G and Leide Svegborn, Sigrid}}, issn = {{0969-8043}}, language = {{eng}}, pages = {{300--307}}, publisher = {{Elsevier}}, series = {{Applied Radiation and Isotopes}}, title = {{Determination of the biodistribution and dosimetry of (123)I-FP-CIT in male patients with suspected Parkinsonism or Lewy body dementia using planar and combined planar and SPECT/CT imaging.}}, url = {{http://dx.doi.org/10.1016/j.apradiso.2013.09.006}}, doi = {{10.1016/j.apradiso.2013.09.006}}, volume = {{82}}, year = {{2013}}, }