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High-energy-density acoustofluidic device using a double-parabolic ultrasonic transducer

Corato, Enrico LU orcid ; Jakobsson, Ola LU ; Qiu, Wei LU orcid ; Morita, Takeshi and Augustsson, Per LU (2025) In Physical Review Applied 23.
Abstract
High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimental characterization of a double-parabolic metallic acoustic waveguide and simulations of its working mechanism in two dimensions. We could focus 4.9-µm polystyrene particles at a flowrate of 5 ml/min, corresponding to an average retention time of 13.5 ms for particles in the actuated area. Moreover, we measured the acoustic energy density in the... (More)
High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimental characterization of a double-parabolic metallic acoustic waveguide and simulations of its working mechanism in two dimensions. We could focus 4.9-µm polystyrene particles at a flowrate of 5 ml/min, corresponding to an average retention time of 13.5 ms for particles in the actuated area. Moreover, we measured the acoustic energy density in the channel at stopped-flow condition, obtaining an average value of 1207 J/m3 and a maximum value of 2977 J/m3 with an input electrical power of 1.5 W. By comparing the simulation results with laser-Doppler vibrometer measurements, we confirmed that transverse sound waves play a significant role in the working mechanism of the double-parabolic structure, thus paving the way for further future optimization of the waveguide design. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Review Applied
volume
23
article number
024031
pages
10 pages
publisher
American Physical Society
external identifiers
  • scopus:85217755893
ISSN
2331-7019
DOI
10.1103/PhysRevApplied.23.024031
language
English
LU publication?
yes
id
42c7012c-ff67-47b1-9198-5550852b24fe
date added to LUP
2025-02-19 01:12:16
date last changed
2025-02-24 04:01:17
@article{42c7012c-ff67-47b1-9198-5550852b24fe,
  abstract     = {{High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimental characterization of a double-parabolic metallic acoustic waveguide and simulations of its working mechanism in two dimensions. We could focus 4.9-µm polystyrene particles at a flowrate of 5 ml/min, corresponding to an average retention time of 13.5 ms for particles in the actuated area. Moreover, we measured the acoustic energy density in the channel at stopped-flow condition, obtaining an average value of 1207 J/m3 and a maximum value of 2977 J/m3 with an input electrical power of 1.5 W. By comparing the simulation results with laser-Doppler vibrometer measurements, we confirmed that transverse sound waves play a significant role in the working mechanism of the double-parabolic structure, thus paving the way for further future optimization of the waveguide design.}},
  author       = {{Corato, Enrico and Jakobsson, Ola and Qiu, Wei and Morita, Takeshi and Augustsson, Per}},
  issn         = {{2331-7019}},
  language     = {{eng}},
  month        = {{02}},
  publisher    = {{American Physical Society}},
  series       = {{Physical Review Applied}},
  title        = {{High-energy-density acoustofluidic device using a double-parabolic ultrasonic transducer}},
  url          = {{http://dx.doi.org/10.1103/PhysRevApplied.23.024031}},
  doi          = {{10.1103/PhysRevApplied.23.024031}},
  volume       = {{23}},
  year         = {{2025}},
}