Suicidal patients are deficient in vitamin D, associated with a pro-inflammatory status in the blood.
Grudet, Cécile LU
; Malm, Johan
LU
; Westrin, Åsa
LU
and Brundin, Lena
LU
(2014)
In Psychoneuroendocrinology
50.
p.210-219
- Abstract
- Low levels of vitamin D may play a role in psychiatric disorders, as cross-sectional studies show an association between vitamin D deficiency and depression, schizophrenia and psychotic symptoms. The underlying mechanisms are not well understood, although vitamin D is known to influence the immune system to promote a T helper (Th)-2 phenotype. At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide. We therefore hypothesized that suicidal patients would be deficient in vitamin D, which could be responsible for the inflammatory changes observed in these patients.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4691155
- author
- Grudet, Cécile
LU
; Malm, Johan
LU
; Westrin, Åsa
LU
and Brundin, Lena
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Psychoneuroendocrinology
- volume
- 50
- pages
- 210 - 219
- publisher
- Elsevier
- external identifiers
-
- pmid:25240206
- wos:000345061000020
- scopus:84908413262
- pmid:25240206
- ISSN
- 1873-3360
- DOI
- 10.1016/j.psyneuen.2014.08.016
- project
- Individanpassad behandling av patienter med depression, med särskilt fokus på suicidrisk.
- language
- English
- LU publication?
- yes
- id
- f9985da7-fb8e-44f5-beee-b9cfd55a9a45 (old id 4691155)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25240206?dopt=Abstract
- date added to LUP
- 2016-04-01 09:52:31
- date last changed
- 2024-02-04 14:03:33
@article{f9985da7-fb8e-44f5-beee-b9cfd55a9a45,
abstract = {{Low levels of vitamin D may play a role in psychiatric disorders, as cross-sectional studies show an association between vitamin D deficiency and depression, schizophrenia and psychotic symptoms. The underlying mechanisms are not well understood, although vitamin D is known to influence the immune system to promote a T helper (Th)-2 phenotype. At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide. We therefore hypothesized that suicidal patients would be deficient in vitamin D, which could be responsible for the inflammatory changes observed in these patients.}},
author = {{Grudet, Cécile and Malm, Johan and Westrin, Åsa and Brundin, Lena}},
issn = {{1873-3360}},
language = {{eng}},
pages = {{210--219}},
publisher = {{Elsevier}},
series = {{Psychoneuroendocrinology}},
title = {{Suicidal patients are deficient in vitamin D, associated with a pro-inflammatory status in the blood.}},
url = {{https://lup.lub.lu.se/search/files/1345764/5322739}},
doi = {{10.1016/j.psyneuen.2014.08.016}},
volume = {{50}},
year = {{2014}},
}