Periodontitis is associated with airflow obstruction in the Malmö Offspring Dental Study
(2024) In Journal of Clinical Periodontology 51(1). p.86-96- Abstract
AIM: To investigate the association between periodontitis and lung function in the Malmö Offspring Dental Study.
MATERIALS AND METHODS: In all 1001 individuals (49.9% female, mean age: 44.6) from Malmö Offspring Dental Study were included. Periodontitis was assessed by a full-mouth examination protocol including bleeding on probing and classified according to the American Academy of Periodontology/Center for Disease Control definitions. Forced expiratory volume in 1 s (FEV1 ) and forced vital capacity (FVC) were expressed as absolute values and %predicted according to Global Lung Function Initiative reference values. FEV1 , FVC and FEV1 /FVC were analysed in relation to periodontal status using linear regression.
RESULTS:... (More)
AIM: To investigate the association between periodontitis and lung function in the Malmö Offspring Dental Study.
MATERIALS AND METHODS: In all 1001 individuals (49.9% female, mean age: 44.6) from Malmö Offspring Dental Study were included. Periodontitis was assessed by a full-mouth examination protocol including bleeding on probing and classified according to the American Academy of Periodontology/Center for Disease Control definitions. Forced expiratory volume in 1 s (FEV1 ) and forced vital capacity (FVC) were expressed as absolute values and %predicted according to Global Lung Function Initiative reference values. FEV1 , FVC and FEV1 /FVC were analysed in relation to periodontal status using linear regression.
RESULTS: Severe periodontitis was found in 7% of the population. Adjusted regression models showed significant associations between lung function and severe periodontitis with 2.1 unit lower FEV1 /FVC ratio (95% CI: -3.91, -0.23) and odds ratio (adjusted) of 2.56 (95% CI: 1.40, 4.75, p = .003) for airflow obstruction (FEV1 /FVC less than the lower limit of normal) if having severe periodontitis. Lower values of %predicted FEV1 and %predicted FVC, but not FEV1 /FVC, were found in individuals with >25% bleeding on probing.
CONCLUSIONS: Severe periodontitis was associated with lower FEV1 /FVC ratio and airflow obstruction in the present cohort. More large-scale prospective studies and intervention studies are required for a comprehensive evaluation.
(Less)
- author
- Røsland, Anders ; Bertelsen, Randi J. ; Bunæs, Dagmar F. ; Drengenes, Christine ; Engström, Gunnar LU ; Klinge, Bjørn ; Lie, Stein Atle ; Nilsson, Peter M. LU ; Jönsson, Daniel LU and Malinovschi, Andrei LU
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Humans, Female, Adult, Male, Pulmonary Disease, Chronic Obstructive/diagnosis, Prospective Studies, Spirometry, Lung, Vital Capacity, Forced Expiratory Volume, Periodontitis/complications
- in
- Journal of Clinical Periodontology
- volume
- 51
- issue
- 1
- pages
- 11 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85174186618
- pmid:37837290
- ISSN
- 0303-6979
- DOI
- 10.1111/jcpe.13886
- language
- English
- LU publication?
- yes
- id
- 4b72cc4c-4693-4668-bc28-6e8f9f2c9d75
- date added to LUP
- 2023-12-14 15:08:10
- date last changed
- 2024-08-03 18:27:08
@article{4b72cc4c-4693-4668-bc28-6e8f9f2c9d75, abstract = {{<p>AIM: To investigate the association between periodontitis and lung function in the Malmö Offspring Dental Study.</p><p>MATERIALS AND METHODS: In all 1001 individuals (49.9% female, mean age: 44.6) from Malmö Offspring Dental Study were included. Periodontitis was assessed by a full-mouth examination protocol including bleeding on probing and classified according to the American Academy of Periodontology/Center for Disease Control definitions. Forced expiratory volume in 1 s (FEV1 ) and forced vital capacity (FVC) were expressed as absolute values and %predicted according to Global Lung Function Initiative reference values. FEV1 , FVC and FEV1 /FVC were analysed in relation to periodontal status using linear regression.</p><p>RESULTS: Severe periodontitis was found in 7% of the population. Adjusted regression models showed significant associations between lung function and severe periodontitis with 2.1 unit lower FEV1 /FVC ratio (95% CI: -3.91, -0.23) and odds ratio (adjusted) of 2.56 (95% CI: 1.40, 4.75, p = .003) for airflow obstruction (FEV1 /FVC less than the lower limit of normal) if having severe periodontitis. Lower values of %predicted FEV1 and %predicted FVC, but not FEV1 /FVC, were found in individuals with >25% bleeding on probing.</p><p>CONCLUSIONS: Severe periodontitis was associated with lower FEV1 /FVC ratio and airflow obstruction in the present cohort. More large-scale prospective studies and intervention studies are required for a comprehensive evaluation.</p>}}, author = {{Røsland, Anders and Bertelsen, Randi J. and Bunæs, Dagmar F. and Drengenes, Christine and Engström, Gunnar and Klinge, Bjørn and Lie, Stein Atle and Nilsson, Peter M. and Jönsson, Daniel and Malinovschi, Andrei}}, issn = {{0303-6979}}, keywords = {{Humans; Female; Adult; Male; Pulmonary Disease, Chronic Obstructive/diagnosis; Prospective Studies; Spirometry; Lung; Vital Capacity; Forced Expiratory Volume; Periodontitis/complications}}, language = {{eng}}, number = {{1}}, pages = {{86--96}}, publisher = {{Wiley-Blackwell}}, series = {{Journal of Clinical Periodontology}}, title = {{Periodontitis is associated with airflow obstruction in the Malmö Offspring Dental Study}}, url = {{http://dx.doi.org/10.1111/jcpe.13886}}, doi = {{10.1111/jcpe.13886}}, volume = {{51}}, year = {{2024}}, }