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Fabrication and characterization of a nanosensor for admittance spectroscopy of biomolecules

Montelius, Lars LU ; Tegenfeldt, Jonas O. LU orcid and Ling, Torbjörn G.I. (1995) In Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films 13(3). p.1755-1760
Abstract

We have fabricated nanometer-sized interdigitated electrode patterns using electron beam lithography and liftoff techniques. The aim of the investigation was to find out whether the dimensions (i.e., the electrode separations) of the pattern would affect the admittance signal of the biomolecules in between the electrodes. Since the admittance signal scales with the geometrical factor A/d, where A is the electrode area and d is the separation, we chose to keep A/d constant when changing the electrode separation in order to eliminate this trivial effect on the admittance signal. An interdigitated electrode structure having an interelectrode spacing in the nanometer regime makes it possible to reach high nonstationary as well as stationary... (More)

We have fabricated nanometer-sized interdigitated electrode patterns using electron beam lithography and liftoff techniques. The aim of the investigation was to find out whether the dimensions (i.e., the electrode separations) of the pattern would affect the admittance signal of the biomolecules in between the electrodes. Since the admittance signal scales with the geometrical factor A/d, where A is the electrode area and d is the separation, we chose to keep A/d constant when changing the electrode separation in order to eliminate this trivial effect on the admittance signal. An interdigitated electrode structure having an interelectrode spacing in the nanometer regime makes it possible to reach high nonstationary as well as stationary electric field strengths while having a low applied voltage level. Hence, electrode reactions will be as small as possible, while a high signal to noise ratio is obtained. We have been able to experimentally study the response of the impedance behavior to high electric fields exhibiting either a positive or a negative shift of the permittivity as a function of the field being a high alternating-current or a direct-current field, respectively.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films
volume
13
issue
3
pages
6 pages
publisher
American Institute of Physics (AIP)
external identifiers
  • scopus:0001554186
ISSN
0734-2101
DOI
10.1116/1.579765
language
English
LU publication?
yes
id
4d2496d2-d329-4e7f-9521-6de0f7d7647b
date added to LUP
2018-10-20 10:58:22
date last changed
2021-06-06 05:17:52
@article{4d2496d2-d329-4e7f-9521-6de0f7d7647b,
  abstract     = {{<p>We have fabricated nanometer-sized interdigitated electrode patterns using electron beam lithography and liftoff techniques. The aim of the investigation was to find out whether the dimensions (i.e., the electrode separations) of the pattern would affect the admittance signal of the biomolecules in between the electrodes. Since the admittance signal scales with the geometrical factor A/d, where A is the electrode area and d is the separation, we chose to keep A/d constant when changing the electrode separation in order to eliminate this trivial effect on the admittance signal. An interdigitated electrode structure having an interelectrode spacing in the nanometer regime makes it possible to reach high nonstationary as well as stationary electric field strengths while having a low applied voltage level. Hence, electrode reactions will be as small as possible, while a high signal to noise ratio is obtained. We have been able to experimentally study the response of the impedance behavior to high electric fields exhibiting either a positive or a negative shift of the permittivity as a function of the field being a high alternating-current or a direct-current field, respectively.</p>}},
  author       = {{Montelius, Lars and Tegenfeldt, Jonas O. and Ling, Torbjörn G.I.}},
  issn         = {{0734-2101}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{3}},
  pages        = {{1755--1760}},
  publisher    = {{American Institute of Physics (AIP)}},
  series       = {{Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films}},
  title        = {{Fabrication and characterization of a nanosensor for admittance spectroscopy of biomolecules}},
  url          = {{http://dx.doi.org/10.1116/1.579765}},
  doi          = {{10.1116/1.579765}},
  volume       = {{13}},
  year         = {{1995}},
}