Effects of neuromuscular electrical stimulation on energy expenditure and postprandial metabolism in healthy men
(2022) In Applied Physiology, Nutrition and Metabolism 47(1). p.27-33- Abstract
It is unclear whether neuromuscular electrical stimulation (NMES) has meaningful metabolic effects when users have the opportunity to self-select the intensity to one that can be comfortably tolerated. Nine healthy men aged 28 6 9y (mean 6 SD) with a body mass index 22.3 6 2.3 kg/m2 completed 3 trials involving a 2-h oral glucose tolerance test whilst, in a randomised counterbalanced order, (1) sitting motionless (SIT), (2) standing motionless (STAND); and (3) sitting motionless with NMES of quadriceps and calves at a self-selected tolerable intensity. The mean (95% confidence interval [CI]) total energy expenditure was greater in the NMES trial (221 [180–262] kcal/2 h) and STAND trial (178 [164–191] kcal/2 h) than during SIT... (More)
It is unclear whether neuromuscular electrical stimulation (NMES) has meaningful metabolic effects when users have the opportunity to self-select the intensity to one that can be comfortably tolerated. Nine healthy men aged 28 6 9y (mean 6 SD) with a body mass index 22.3 6 2.3 kg/m2 completed 3 trials involving a 2-h oral glucose tolerance test whilst, in a randomised counterbalanced order, (1) sitting motionless (SIT), (2) standing motionless (STAND); and (3) sitting motionless with NMES of quadriceps and calves at a self-selected tolerable intensity. The mean (95% confidence interval [CI]) total energy expenditure was greater in the NMES trial (221 [180–262] kcal/2 h) and STAND trial (178 [164–191] kcal/2 h) than during SIT (159 [150–167] kcal/2 h) (both, p < 0.05). This was primarily driven by an increase in carbohydrate oxidation in the NMES and STAND trials compared with the SIT trial (p < 0.05). Postprandial insulin iAUC was lower in both NMES and STAND compared with SIT (16.4 [7.7–25.1], 17 [7–27] and 22.6 [10.8–34.4] nmol·120 min/L, respectively; both, p < 0.05). Compared with sitting, both NMES and STAND increased energy expenditure and whole-body carbohydrate oxidation and reduced postprandial insulin concentrations in healthy men, with more pronounced effects seen with NMES. Self-selected NMES is a potential strategy for improving metabolic health. This trial is registered at ClinicalTrials.gov (ID: NCT04389736). Novelty: • NMES at a comfortable intensity enhances energy expenditure and carbohydrate oxidation, and reduces postprandial insulinemia. • Thus, self-selected NMES represents a potential strategy to improve metabolic health.
(Less)
- author
- Chen, Yung Chih
; Davies, Russell G.
; Hengist, Aaron
; Carroll, Harriet A.
LU
; Perkin, Oliver J. ; Betts, James A. and Thompson, Dylan
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Carbohydrate oxidation, Glucose control, Insulin resistance, NMES, Standing
- in
- Applied Physiology, Nutrition and Metabolism
- volume
- 47
- issue
- 1
- pages
- 7 pages
- publisher
- National Research Council Canada
- external identifiers
-
- scopus:85122481565
- pmid:34403626
- ISSN
- 1715-5312
- DOI
- 10.1139/apnm-2021-0361
- language
- English
- LU publication?
- yes
- id
- 50fdfab3-3b4f-4568-a6f8-daef2de4a02d
- date added to LUP
- 2022-03-01 10:04:24
- date last changed
- 2024-06-27 12:34:32
@article{50fdfab3-3b4f-4568-a6f8-daef2de4a02d, abstract = {{<p>It is unclear whether neuromuscular electrical stimulation (NMES) has meaningful metabolic effects when users have the opportunity to self-select the intensity to one that can be comfortably tolerated. Nine healthy men aged 28 6 9y (mean 6 SD) with a body mass index 22.3 6 2.3 kg/m<sup>2</sup> completed 3 trials involving a 2-h oral glucose tolerance test whilst, in a randomised counterbalanced order, (1) sitting motionless (SIT), (2) standing motionless (STAND); and (3) sitting motionless with NMES of quadriceps and calves at a self-selected tolerable intensity. The mean (95% confidence interval [CI]) total energy expenditure was greater in the NMES trial (221 [180–262] kcal/2 h) and STAND trial (178 [164–191] kcal/2 h) than during SIT (159 [150–167] kcal/2 h) (both, p < 0.05). This was primarily driven by an increase in carbohydrate oxidation in the NMES and STAND trials compared with the SIT trial (p < 0.05). Postprandial insulin iAUC was lower in both NMES and STAND compared with SIT (16.4 [7.7–25.1], 17 [7–27] and 22.6 [10.8–34.4] nmol·120 min/L, respectively; both, p < 0.05). Compared with sitting, both NMES and STAND increased energy expenditure and whole-body carbohydrate oxidation and reduced postprandial insulin concentrations in healthy men, with more pronounced effects seen with NMES. Self-selected NMES is a potential strategy for improving metabolic health. This trial is registered at ClinicalTrials.gov (ID: NCT04389736). Novelty: • NMES at a comfortable intensity enhances energy expenditure and carbohydrate oxidation, and reduces postprandial insulinemia. • Thus, self-selected NMES represents a potential strategy to improve metabolic health.</p>}}, author = {{Chen, Yung Chih and Davies, Russell G. and Hengist, Aaron and Carroll, Harriet A. and Perkin, Oliver J. and Betts, James A. and Thompson, Dylan}}, issn = {{1715-5312}}, keywords = {{Carbohydrate oxidation; Glucose control; Insulin resistance; NMES; Standing}}, language = {{eng}}, number = {{1}}, pages = {{27--33}}, publisher = {{National Research Council Canada}}, series = {{Applied Physiology, Nutrition and Metabolism}}, title = {{Effects of neuromuscular electrical stimulation on energy expenditure and postprandial metabolism in healthy men}}, url = {{http://dx.doi.org/10.1139/apnm-2021-0361}}, doi = {{10.1139/apnm-2021-0361}}, volume = {{47}}, year = {{2022}}, }