Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Comparing dose response of cancer incidence in Sweden after the Chernobyl Nuclear Power Plant accident with Life Span Study of atomic bomb survivors

Tondel, Martin ; Nordquist, Tobias ; Isaksson, Mats ; Rääf, Christopher LU orcid and Wålinder, Robert (2025) In Radiation Protection Dosimetry 201(16). p.1125-1130
Abstract

Follow-up of the atomic bomb survivors in Japan in the Life Span Study (LSS) has been fundamental for the understanding of the dose–response curve. We compare our risk estimates from a newly published epidemiological study on cancer in Sweden after the Chernobyl Nuclear Power Plant accident with the LSS data. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) were calculated using conditional logistic regression adjusted for rural/nonrural habitat, education level, and pre-Chernobyl cancer incidence from 1980 to 1985, respectively. Adjusted HRs by sex were calculated in deciles for all cancer sites combined for 1986 to 2020. These risk estimates were translated to excess relative risk (ERR) to allow comparison with LSS... (More)

Follow-up of the atomic bomb survivors in Japan in the Life Span Study (LSS) has been fundamental for the understanding of the dose–response curve. We compare our risk estimates from a newly published epidemiological study on cancer in Sweden after the Chernobyl Nuclear Power Plant accident with the LSS data. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) were calculated using conditional logistic regression adjusted for rural/nonrural habitat, education level, and pre-Chernobyl cancer incidence from 1980 to 1985, respectively. Adjusted HRs by sex were calculated in deciles for all cancer sites combined for 1986 to 2020. These risk estimates were translated to excess relative risk (ERR) to allow comparison with LSS incidence data. ERRs per decile were compatible with ERR in the low-dose range <100 mGy for both sexes. The CIs in each decile need to be taken into account when interpreting the dose–response curve. Risk estimates in dose categories add important information at very low doses on the dose–response curve when compared to LSS data.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Radiation Protection Dosimetry
volume
201
issue
16
pages
6 pages
publisher
Oxford University Press
external identifiers
  • pmid:40838680
  • scopus:105017899647
ISSN
0144-8420
DOI
10.1093/rpd/ncaf097
language
English
LU publication?
yes
id
51d65486-0c53-4d50-bc2d-442adf734820
date added to LUP
2025-11-25 12:07:29
date last changed
2025-12-23 15:17:28
@misc{51d65486-0c53-4d50-bc2d-442adf734820,
  abstract     = {{<p>Follow-up of the atomic bomb survivors in Japan in the Life Span Study (LSS) has been fundamental for the understanding of the dose–response curve. We compare our risk estimates from a newly published epidemiological study on cancer in Sweden after the Chernobyl Nuclear Power Plant accident with the LSS data. Hazard ratios (HRs) with 95% confidence intervals (95% CIs) were calculated using conditional logistic regression adjusted for rural/nonrural habitat, education level, and pre-Chernobyl cancer incidence from 1980 to 1985, respectively. Adjusted HRs by sex were calculated in deciles for all cancer sites combined for 1986 to 2020. These risk estimates were translated to excess relative risk (ERR) to allow comparison with LSS incidence data. ERRs per decile were compatible with ERR in the low-dose range &lt;100 mGy for both sexes. The CIs in each decile need to be taken into account when interpreting the dose–response curve. Risk estimates in dose categories add important information at very low doses on the dose–response curve when compared to LSS data.</p>}},
  author       = {{Tondel, Martin and Nordquist, Tobias and Isaksson, Mats and Rääf, Christopher and Wålinder, Robert}},
  issn         = {{0144-8420}},
  language     = {{eng}},
  number       = {{16}},
  pages        = {{1125--1130}},
  publisher    = {{Oxford University Press}},
  series       = {{Radiation Protection Dosimetry}},
  title        = {{Comparing dose response of cancer incidence in Sweden after the Chernobyl Nuclear Power Plant accident with Life Span Study of atomic bomb survivors}},
  url          = {{http://dx.doi.org/10.1093/rpd/ncaf097}},
  doi          = {{10.1093/rpd/ncaf097}},
  volume       = {{201}},
  year         = {{2025}},
}