Lund University Publications

@article{5f67d27d-410a-48f1-a059-db4387d7c451,
  abstract     = {{<p>Background and Aims: Plant-forward dietary patterns have been associated with cardiometabolic health benefits, which, in turn, have been related to cognitive performance with inconsistent findings. The objective of this study was to examine the relationship between baseline adherence to three a priori dietary patterns (Mediterranean, DASH, and MIND diets) with 2-year changes in cognitive performance in older adults with overweight or obesity and high cardiovascular disease risk. Methods: A prospective cohort analysis was conducted within the PREDIMED-Plus trial, involving 6,647 men and women aged 55–75 years with overweight or obesity and metabolic syndrome. Using a validated, semiquantitative 143-item food frequency questionnaire completed at baseline, the dietary pattern adherence scores were calculated. An extensive neuropsychological test battery was administered at baseline and 2-year follow-up. Multivariable-adjusted linear regression models were used to assess associations between 2-year changes in cognitive function z-scores across tertiles of baseline adherence to the a priori dietary patterns. Results: Adherence to the Mediterranean diet at baseline was associated with 2-year changes in the general cognitive screening Mini-Mental State Examination (MMSE, β: 0.070; 95% CI: 0.014, 0.175, P-trend = 0.011), and two executive function-related assessments: the Trail Making Tests Part A (TMT-A, β: −0.054; 95% CI: −0.110, − 0.002, P-trend = 0.047) and Part B (TMT-B, β: −0.079; 95% CI: −0.134, −0.024, P-trend = 0.004). Adherence to the MIND diet was associated with the backward recall Digit Span Test assessment of working memory (DST-B, β: 0.058; 95% CI: 0.002, 0.114, P-trend = 0.045). However, higher adherence to the DASH dietary pattern was not associated with better cognitive function over a period of 2 years. Conclusion: In older Spanish individuals with overweight or obesity and at high cardiovascular disease risk, higher baseline adherence to the Mediterranean dietary pattern may be associated with better cognitive performance than lower adherence over a period of 2 years.</p>}},
  author       = {{Nishi, Stephanie K. and Babio, Nancy and Gómez-Martínez, Carlos and Martínez-González, Miguel Ángel and Ros, Emilio and Corella, Dolores and Castañer, Olga and Martínez, J. Alfredo and Alonso-Gómez, Ángel M. and Wärnberg, Julia and Vioque, Jesús and Romaguera, Dora and López-Miranda, José and Estruch, Ramon and Tinahones, Francisco J. and Lapetra, José and Serra-Majem, J. Luís and Bueno-Cavanillas, Aurora and Tur, Josep A. and Martín Sánchez, Vicente and Pintó, Xavier and Delgado-Rodríguez, Miguel and Matía-Martín, Pilar and Vidal, Josep and Vázquez, Clotilde and Daimiel, Lidia and Razquin, Cristina and Coltell, Oscar and Becerra-Tomás, Nerea and De La Torre Fornell, Rafael and Abete, Itziar and Sorto-Sanchez, Carolina and Barón-López, Francisco Javier and Signes-Pastor, Antonio José and Konieczna, Jadwiga and Garcia-Rios, Antonio and Casas, Rosa and Gomez-Perez, Ana Maria and Santos-Lozano, José Manuel and García-Arellano, Ana and Guillem-Saiz, Patricia and Ni, Jiaqi and Trinidad Soria-Florido, Maria and Zulet, M. Ángeles and Vaquero-Luna, Jessica and Toledo, Estefanía and Fitó, Montserrat and Salas-Salvadó, Jordi}},
  issn         = {{1663-4365}},
  keywords     = {{cognition; DASH diet; dietary pattern; Mediterranean diet (MedDiet); MIND diet}},
  language     = {{eng}},
  month        = {{12}},
  publisher    = {{Frontiers Media S. A.}},
  series       = {{Frontiers in Aging Neuroscience}},
  title        = {{Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function : The 2-Year Longitudinal Changes in an Older Spanish Cohort}},
  url          = {{http://dx.doi.org/10.3389/fnagi.2021.782067}},
  doi          = {{10.3389/fnagi.2021.782067}},
  volume       = {{13}},
  year         = {{2021}},
}