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Racial Disparities in Mortality During the 1918 Influenza Pandemic in United States Cities

Eiermann, Martin ; Wrigley-Field, Elizabeth ; Feigenbaum, James J ; Helgertz, Jonas LU ; Hernandez, Elaine and Boen, Courtney E (2022) In Demography 59(5). p.1953-1979
Abstract
Against a backdrop of extreme racial health inequality, the 1918 influenza pandemic resulted in a striking reduction of non-White to White influenza and pneumonia mortality disparities in United States cities. We provide the most complete account to date of these reduced racial disparities, showing that they were unexpectedly uniform across cities. Linking data from multiple sources, we then examine potential explanations for this finding, including city-level sociodemographic factors such as segregation, implementation of nonpharmaceutical interventions, racial differences in exposure to the milder spring 1918 “herald wave,” and racial differences in early-life influenza exposures, resulting in differential immunological vulnerability to... (More)
Against a backdrop of extreme racial health inequality, the 1918 influenza pandemic resulted in a striking reduction of non-White to White influenza and pneumonia mortality disparities in United States cities. We provide the most complete account to date of these reduced racial disparities, showing that they were unexpectedly uniform across cities. Linking data from multiple sources, we then examine potential explanations for this finding, including city-level sociodemographic factors such as segregation, implementation of nonpharmaceutical interventions, racial differences in exposure to the milder spring 1918 “herald wave,” and racial differences in early-life influenza exposures, resulting in differential immunological vulnerability to the 1918 flu. While we find little evidence for the first three explanations, we offer suggestive evidence that racial variation in childhood exposure to the 1889–1892 influenza pandemic may have shrunk racial disparities in 1918. We also highlight the possibility that differential behavioral responses to the herald wave may have protected non-White urban populations. By providing a comprehensive description and examination of racial inequality in mortality during the 1918 pandemic, we offer a framework for understanding disparities in infectious disease mortality that considers interactions between the natural histories of particular microbial agents and the social histories of those they infect. (Less)
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
1918 influenza pandemic, Racial disparaties, Immunological imprinting, nonpharmaceutical intervention, residential segregation
in
Demography
volume
59
issue
5
pages
1953 - 1979
publisher
Population Assn Amer
external identifiers
  • pmid:36124998
  • scopus:85139442647
ISSN
0070-3370
DOI
10.1215/00703370-10235825
language
English
LU publication?
yes
id
6e4969f5-a169-4531-9321-01b85698f977
date added to LUP
2022-09-22 16:31:39
date last changed
2022-11-08 04:08:41
@article{6e4969f5-a169-4531-9321-01b85698f977,
  abstract     = {{Against a backdrop of extreme racial health inequality, the 1918 influenza pandemic resulted in a striking reduction of non-White to White influenza and pneumonia mortality disparities in United States cities. We provide the most complete account to date of these reduced racial disparities, showing that they were unexpectedly uniform across cities. Linking data from multiple sources, we then examine potential explanations for this finding, including city-level sociodemographic factors such as segregation, implementation of nonpharmaceutical interventions, racial differences in exposure to the milder spring 1918 “herald wave,” and racial differences in early-life influenza exposures, resulting in differential immunological vulnerability to the 1918 flu. While we find little evidence for the first three explanations, we offer suggestive evidence that racial variation in childhood exposure to the 1889–1892 influenza pandemic may have shrunk racial disparities in 1918. We also highlight the possibility that differential behavioral responses to the herald wave may have protected non-White urban populations. By providing a comprehensive description and examination of racial inequality in mortality during the 1918 pandemic, we offer a framework for understanding disparities in infectious disease mortality that considers interactions between the natural histories of particular microbial agents and the social histories of those they infect.}},
  author       = {{Eiermann, Martin and Wrigley-Field, Elizabeth and Feigenbaum, James J and Helgertz, Jonas and Hernandez, Elaine and Boen, Courtney E}},
  issn         = {{0070-3370}},
  keywords     = {{1918 influenza pandemic; Racial disparaties; Immunological imprinting; nonpharmaceutical intervention; residential segregation}},
  language     = {{eng}},
  month        = {{09}},
  number       = {{5}},
  pages        = {{1953--1979}},
  publisher    = {{Population Assn Amer}},
  series       = {{Demography}},
  title        = {{Racial Disparities in Mortality During the 1918 Influenza Pandemic in United States Cities}},
  url          = {{http://dx.doi.org/10.1215/00703370-10235825}},
  doi          = {{10.1215/00703370-10235825}},
  volume       = {{59}},
  year         = {{2022}},
}