Sources of Parent-Child Transmission of Drug Abuse : Path Analyses of Not-Lived-With Parental, Stepparental, Triparental, and Adoptive Families
(2018) In Journal of Nervous and Mental Disease 206(4). p.239-244- Abstract
To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the effects of genes + rearing, genes only, and rearing only. The estimates of parent-offspring correlations were statistically homogenous across family types. The weighted estimate of the father-offspring correlation for DA for genes + rearing, genes-only, and rearing-only relationships were, respectively, +0.26, +0.19, and +0.06. Parallel figures... (More)
To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the effects of genes + rearing, genes only, and rearing only. The estimates of parent-offspring correlations were statistically homogenous across family types. The weighted estimate of the father-offspring correlation for DA for genes + rearing, genes-only, and rearing-only relationships were, respectively, +0.26, +0.19, and +0.06. Parallel figures for mother-offspring relationships were +0.19, +0.13, and +0.09. In both genes + rearing and genes-only parent-offspring relationships, DA correlations were stronger for fathers than for mothers. Both genetic and environmental factors contribute substantially to parent-offspring resemblance for DA and seem to be additive.
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- author
- Kendler, Kenneth S. LU ; Ohlsson, Henrik LU ; Sundquist, Kristina LU and Sundquist, Jan LU
- organization
- publishing date
- 2018-04-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Drug abuse, environment, genetics, parent-offspring, rearing, Sweden
- in
- Journal of Nervous and Mental Disease
- volume
- 206
- issue
- 4
- pages
- 6 pages
- publisher
- Wolters Kluwer
- external identifiers
-
- pmid:29252928
- scopus:85045440027
- ISSN
- 0022-3018
- DOI
- 10.1097/NMD.0000000000000775
- language
- English
- LU publication?
- yes
- id
- 7375ffa1-7e88-4dd6-a51e-0856ff63ecc6
- date added to LUP
- 2018-04-25 16:25:12
- date last changed
- 2024-07-08 13:14:46
@article{7375ffa1-7e88-4dd6-a51e-0856ff63ecc6, abstract = {{<p>To clarify the origins of parent-child resemblance for drug abuse (DA), using national Swedish data, we fit path models to information on DA in parents and children from six informative family types: i) not-lived-with father, ii) not-lived-with mother, iii) stepfather, iv) stepmother, v) triparental, and vi) adoptive. From these families, we estimated parent-offspring resemblance reflecting the effects of genes + rearing, genes only, and rearing only. The estimates of parent-offspring correlations were statistically homogenous across family types. The weighted estimate of the father-offspring correlation for DA for genes + rearing, genes-only, and rearing-only relationships were, respectively, +0.26, +0.19, and +0.06. Parallel figures for mother-offspring relationships were +0.19, +0.13, and +0.09. In both genes + rearing and genes-only parent-offspring relationships, DA correlations were stronger for fathers than for mothers. Both genetic and environmental factors contribute substantially to parent-offspring resemblance for DA and seem to be additive.</p>}}, author = {{Kendler, Kenneth S. and Ohlsson, Henrik and Sundquist, Kristina and Sundquist, Jan}}, issn = {{0022-3018}}, keywords = {{Drug abuse; environment; genetics; parent-offspring; rearing; Sweden}}, language = {{eng}}, month = {{04}}, number = {{4}}, pages = {{239--244}}, publisher = {{Wolters Kluwer}}, series = {{Journal of Nervous and Mental Disease}}, title = {{Sources of Parent-Child Transmission of Drug Abuse : Path Analyses of Not-Lived-With Parental, Stepparental, Triparental, and Adoptive Families}}, url = {{http://dx.doi.org/10.1097/NMD.0000000000000775}}, doi = {{10.1097/NMD.0000000000000775}}, volume = {{206}}, year = {{2018}}, }