Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects
(2005) In Drug Discovery Today: Technologies 2(4). p.345-351- Abstract
- Biomarker discovery is dependent upon two disciplines: the field of clinical bioanalysis linked to disease aetiology and the application of high level technology platforms for identifying proteins/peptides in complex samples. However, diagnostic biomarker measurements require certain definitions of context that can only be achieved by combining protein science with clinical science. The evaluation of biomarkers requires careful attention to match (1) a specific biological question with (2) the appropriate clinical sample and (3) high resolution technology systems which link protein identities to clinical informatics.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/744168
- author
- Fehniger, Thomas E. ; Laurell, Thomas LU and Marko-Varga, György LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Drug Discovery Today: Technologies
- volume
- 2
- issue
- 4
- pages
- 345 - 351
- publisher
- Elsevier
- external identifiers
-
- scopus:30944439263
- ISSN
- 1740-6749
- DOI
- 10.1016/j.ddtec.2005.11.005
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biomedical Engineering (011200011), Analytical Chemistry (S/LTH) (011001004)
- id
- 2fbc1004-d382-4dc5-b40d-63e755760185 (old id 744168)
- date added to LUP
- 2016-04-04 09:06:20
- date last changed
- 2022-01-29 08:17:25
@article{2fbc1004-d382-4dc5-b40d-63e755760185, abstract = {{Biomarker discovery is dependent upon two disciplines: the field of clinical bioanalysis linked to disease aetiology and the application of high level technology platforms for identifying proteins/peptides in complex samples. However, diagnostic biomarker measurements require certain definitions of context that can only be achieved by combining protein science with clinical science. The evaluation of biomarkers requires careful attention to match (1) a specific biological question with (2) the appropriate clinical sample and (3) high resolution technology systems which link protein identities to clinical informatics.}}, author = {{Fehniger, Thomas E. and Laurell, Thomas and Marko-Varga, György}}, issn = {{1740-6749}}, language = {{eng}}, number = {{4}}, pages = {{345--351}}, publisher = {{Elsevier}}, series = {{Drug Discovery Today: Technologies}}, title = {{Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects}}, url = {{http://dx.doi.org/10.1016/j.ddtec.2005.11.005}}, doi = {{10.1016/j.ddtec.2005.11.005}}, volume = {{2}}, year = {{2005}}, }