Left and Right Atrial Contribution to the P-wave in Realistic Computational Models
(2015) 8th International Conference on Functional Imaging and Modeling of the Heart(FIMH) 9126. p.439-447- Abstract
- ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to simulate P-waves originating from the left atrium (LA) and the right atrium (RA) separately in two realistic models. LA contribution to the P-wave integral was limited to 30% or less. Around 20% could be attributed to the first third of the P-wave which reflected almost only RA depolarization. Both atria contributed to the second and last third... (More)
- ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to simulate P-waves originating from the left atrium (LA) and the right atrium (RA) separately in two realistic models. LA contribution to the P-wave integral was limited to 30% or less. Around 20% could be attributed to the first third of the P-wave which reflected almost only RA depolarization. Both atria contributed to the second and last third with RA contribution being about twice as large as LA contribution. Our results foster the comprehension of the difficulties related to ECG-based LA assessment. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8386446
- author
- Loewe, Axel ; Krueger, Martin W. ; Platonov, Pyotr LU ; Holmqvist, Fredrik LU ; Doessel, Olaf and Seemann, Gunnar
- organization
- publishing date
- 2015
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- atrial enlargement, Left, Mathematical modeling, P-wave, Electrocardiogram, Atrial modeling
- host publication
- Lecture Notes in Computer Science
- volume
- 9126
- pages
- 439 - 447
- publisher
- Springer
- conference name
- 8th International Conference on Functional Imaging and Modeling of the Heart(FIMH)
- conference location
- Maastricht, Netherlands
- conference dates
- 2015-06-25 - 2015-06-27
- external identifiers
-
- wos:000364538500050
- scopus:84949936930
- ISSN
- 0302-9743
- 1611-3349
- DOI
- 10.1007/978-3-319-20309-6_50
- language
- English
- LU publication?
- yes
- id
- 7d60b886-8dcc-4b04-a6c0-f31339fee203 (old id 8386446)
- date added to LUP
- 2016-04-01 09:53:11
- date last changed
- 2024-08-12 08:17:24
@inproceedings{7d60b886-8dcc-4b04-a6c0-f31339fee203, abstract = {{ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to simulate P-waves originating from the left atrium (LA) and the right atrium (RA) separately in two realistic models. LA contribution to the P-wave integral was limited to 30% or less. Around 20% could be attributed to the first third of the P-wave which reflected almost only RA depolarization. Both atria contributed to the second and last third with RA contribution being about twice as large as LA contribution. Our results foster the comprehension of the difficulties related to ECG-based LA assessment.}}, author = {{Loewe, Axel and Krueger, Martin W. and Platonov, Pyotr and Holmqvist, Fredrik and Doessel, Olaf and Seemann, Gunnar}}, booktitle = {{Lecture Notes in Computer Science}}, issn = {{0302-9743}}, keywords = {{atrial enlargement; Left; Mathematical modeling; P-wave; Electrocardiogram; Atrial modeling}}, language = {{eng}}, pages = {{439--447}}, publisher = {{Springer}}, title = {{Left and Right Atrial Contribution to the P-wave in Realistic Computational Models}}, url = {{http://dx.doi.org/10.1007/978-3-319-20309-6_50}}, doi = {{10.1007/978-3-319-20309-6_50}}, volume = {{9126}}, year = {{2015}}, }