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The role of oxidative stress on the pathophysiology of metabolic syndrome

Francisqueti, Fabiane Valentini ; Chiaverini, Lidiana Camargo Talon ; Santos, Klinsmann Carolo Dos LU ; Minatel, Igor Otávio ; Ronchi, Carolina Berchieri ; Ferron, Artur Junio Togneri ; Ferreira, Ana Lúcia A and Corrêa, Camila Renata (2017) In Revista da Associacao Medica Brasileira 63(1). p.85-91
Abstract

Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal adipose tissue, which is metabolically more active, containing a greater amount of resident macrophages compared to other fat deposits. Abdominal adiposity promotes inflammation and oxidative stress, which are precursors of various complications involving MetS components, namely insulin resistance, hypertension and hyperlipidemia. One way to block the effects of oxidative stress would be through the antioxidant defense system, which offsets the excess free radicals. It is known that individuals with metabolic... (More)

Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal adipose tissue, which is metabolically more active, containing a greater amount of resident macrophages compared to other fat deposits. Abdominal adiposity promotes inflammation and oxidative stress, which are precursors of various complications involving MetS components, namely insulin resistance, hypertension and hyperlipidemia. One way to block the effects of oxidative stress would be through the antioxidant defense system, which offsets the excess free radicals. It is known that individuals with metabolic syndrome and obesity have high consumption of fats and sugars originated from processed foods containing high levels of sodium as well as low intake of fruits and vegetables, thus maintaining a state of oxidative stress, that can speed up the onset of MetS. Healthy eating habits could prevent or delay MetS by adding antioxidant-rich foods into the diet.

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author
; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biomarkers/metabolism, Feeding Behavior/physiology, Humans, Metabolic Syndrome/physiopathology, Obesity/physiopathology, Oxidative Stress/physiology
in
Revista da Associacao Medica Brasileira
volume
63
issue
1
pages
7 pages
publisher
Associacao Medica Brasileira
external identifiers
  • scopus:85016021471
  • pmid:28225880
ISSN
0104-4230
DOI
10.1590/1806-9282.63.01.85
language
English
LU publication?
no
id
90730454-f145-4239-89b9-77e792e8a31f
date added to LUP
2019-03-28 18:19:13
date last changed
2024-06-11 07:19:17
@article{90730454-f145-4239-89b9-77e792e8a31f,
  abstract     = {{<p>Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal adipose tissue, which is metabolically more active, containing a greater amount of resident macrophages compared to other fat deposits. Abdominal adiposity promotes inflammation and oxidative stress, which are precursors of various complications involving MetS components, namely insulin resistance, hypertension and hyperlipidemia. One way to block the effects of oxidative stress would be through the antioxidant defense system, which offsets the excess free radicals. It is known that individuals with metabolic syndrome and obesity have high consumption of fats and sugars originated from processed foods containing high levels of sodium as well as low intake of fruits and vegetables, thus maintaining a state of oxidative stress, that can speed up the onset of MetS. Healthy eating habits could prevent or delay MetS by adding antioxidant-rich foods into the diet.</p>}},
  author       = {{Francisqueti, Fabiane Valentini and Chiaverini, Lidiana Camargo Talon and Santos, Klinsmann Carolo Dos and Minatel, Igor Otávio and Ronchi, Carolina Berchieri and Ferron, Artur Junio Togneri and Ferreira, Ana Lúcia A and Corrêa, Camila Renata}},
  issn         = {{0104-4230}},
  keywords     = {{Biomarkers/metabolism; Feeding Behavior/physiology; Humans; Metabolic Syndrome/physiopathology; Obesity/physiopathology; Oxidative Stress/physiology}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{1}},
  pages        = {{85--91}},
  publisher    = {{Associacao Medica Brasileira}},
  series       = {{Revista da Associacao Medica Brasileira}},
  title        = {{The role of oxidative stress on the pathophysiology of metabolic syndrome}},
  url          = {{http://dx.doi.org/10.1590/1806-9282.63.01.85}},
  doi          = {{10.1590/1806-9282.63.01.85}},
  volume       = {{63}},
  year         = {{2017}},
}