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Effect of Food Intake on Vortex Formation Time as a Measurement of Diastolic Left Ventricular Function

Smith, Sarah ; Malmgren, Andreas LU ; Gårdinger, Ylva LU ; Hlebowicz, Joanna LU and Dencker, Magnus LU (2025) In Journal of Clinical Medicine 14(16).
Abstract

Objectives: The aim of the present study was to assess if vortex formation time (VFT) as a measurement of left ventricular (LV) diastolic function is affected by food intake and related to age and sex. Methods: Healthy participants were divided into two age groups: younger (median age: 25 years) and older (median age: 68 years). Transthoracic echocardiography (TTE) examinations were performed during fasting as well as 30 min after a standardized meal. Measurements of the TTE images were performed off-line for the calculation of VFT. Results: There were no differences in VFT between men and women regardless of age. There was a significant increase in VFT from a median value of 2.0 (1.5-2.5) to a median value of 2.3 (1.5-2.0) after food... (More)

Objectives: The aim of the present study was to assess if vortex formation time (VFT) as a measurement of left ventricular (LV) diastolic function is affected by food intake and related to age and sex. Methods: Healthy participants were divided into two age groups: younger (median age: 25 years) and older (median age: 68 years). Transthoracic echocardiography (TTE) examinations were performed during fasting as well as 30 min after a standardized meal. Measurements of the TTE images were performed off-line for the calculation of VFT. Results: There were no differences in VFT between men and women regardless of age. There was a significant increase in VFT from a median value of 2.0 (1.5-2.5) to a median value of 2.3 (1.5-2.0) after food intake in the older study group (p < 0.001). This was not observed in the younger study group, which had a median value of VFT of 2.5 (2.1-3.0) before food intake and a median value of VFT of 2.5 (2.2-3.1) after food intake (p = 0.369). Furthermore, VFT was significantly higher in the younger study group, i.e., 2.5 (2.1-3.0), compared to the older study group, i.e., 2.0 (1.5-2.5), before food intake (p = 0.011), but not after food intake, with a median value of VFT in the younger group of 2.5 (2.2-3.1) and the older group of 2.3 (1.5-2.9) (p = 0.172). Conclusions: Our findings suggest that VFT is affected by age, not by sex. Moreover, VFT is affected by food intake only in elderly subjects.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Medicine
volume
14
issue
16
article number
5783
publisher
MDPI AG
external identifiers
  • pmid:40869610
  • scopus:105014326931
ISSN
2077-0383
DOI
10.3390/jcm14165783
language
English
LU publication?
yes
id
9289442a-3ced-4302-a105-56efce8efc19
date added to LUP
2025-10-21 12:38:49
date last changed
2025-11-05 04:57:00
@article{9289442a-3ced-4302-a105-56efce8efc19,
  abstract     = {{<p>Objectives: The aim of the present study was to assess if vortex formation time (VFT) as a measurement of left ventricular (LV) diastolic function is affected by food intake and related to age and sex. Methods: Healthy participants were divided into two age groups: younger (median age: 25 years) and older (median age: 68 years). Transthoracic echocardiography (TTE) examinations were performed during fasting as well as 30 min after a standardized meal. Measurements of the TTE images were performed off-line for the calculation of VFT. Results: There were no differences in VFT between men and women regardless of age. There was a significant increase in VFT from a median value of 2.0 (1.5-2.5) to a median value of 2.3 (1.5-2.0) after food intake in the older study group (p &lt; 0.001). This was not observed in the younger study group, which had a median value of VFT of 2.5 (2.1-3.0) before food intake and a median value of VFT of 2.5 (2.2-3.1) after food intake (p = 0.369). Furthermore, VFT was significantly higher in the younger study group, i.e., 2.5 (2.1-3.0), compared to the older study group, i.e., 2.0 (1.5-2.5), before food intake (p = 0.011), but not after food intake, with a median value of VFT in the younger group of 2.5 (2.2-3.1) and the older group of 2.3 (1.5-2.9) (p = 0.172). Conclusions: Our findings suggest that VFT is affected by age, not by sex. Moreover, VFT is affected by food intake only in elderly subjects.</p>}},
  author       = {{Smith, Sarah and Malmgren, Andreas and Gårdinger, Ylva and Hlebowicz, Joanna and Dencker, Magnus}},
  issn         = {{2077-0383}},
  language     = {{eng}},
  month        = {{08}},
  number       = {{16}},
  publisher    = {{MDPI AG}},
  series       = {{Journal of Clinical Medicine}},
  title        = {{Effect of Food Intake on Vortex Formation Time as a Measurement of Diastolic Left Ventricular Function}},
  url          = {{http://dx.doi.org/10.3390/jcm14165783}},
  doi          = {{10.3390/jcm14165783}},
  volume       = {{14}},
  year         = {{2025}},
}