Ny in vitro-analys prövad: Blödningstid fortfarande bästa metod för test av den primära hemostasen
(2001) In Lakartidningen 98(37). p.4-3922- Abstract
The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples from healthy controls and from patients with von Willebrand disease or platelet disorders. It is shown that the PFA-100 system has a high sensitivity for von Willebrands disease, while the sensitivity for hereditary platelet dysfunction is low. In its present design this new device could not replace the template bleeding time as a screening test... (More)
The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples from healthy controls and from patients with von Willebrand disease or platelet disorders. It is shown that the PFA-100 system has a high sensitivity for von Willebrands disease, while the sensitivity for hereditary platelet dysfunction is low. In its present design this new device could not replace the template bleeding time as a screening test for primary hemostasis.
(Less)
- author
- Ridefelt, P ; Egberg, N ; Hillarp, A LU ; Lethagen, S LU and Tengborn, L LU
- organization
- alternative title
- New in vitro analysis tested : bleeding time is still the best method for evaluation of primary hemostasis
- publishing date
- 2001-09-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bleeding Time/methods, Blood Platelet Disorders/blood, Hemostasis, Humans, Platelet Function Tests/instrumentation, Sensitivity and Specificity
- in
- Lakartidningen
- volume
- 98
- issue
- 37
- pages
- 4 - 3922
- publisher
- Swedish Medical Association
- external identifiers
-
- pmid:11586831
- scopus:0035850657
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- yes
- id
- 9492f2ed-cbf8-4f1f-a5da-40a6e9d09f52
- alternative location
- https://lakartidningen.se/wp-content/uploads/OldPdfFiles/2001/23402.pdf
- date added to LUP
- 2022-08-29 10:22:41
- date last changed
- 2025-04-04 23:49:05
@article{9492f2ed-cbf8-4f1f-a5da-40a6e9d09f52,
abstract = {{<p>The need is great for a simple, cheap and readily accessible method for the evaluation of primary hemostasis in work-ups at both out-patient clinics and units caring for surgical or intensive care patients. PFA-100 is a recently introduced instrument for in vitro testing of platelet function. We report experiences from Stockholm, Gothenburg and Malmo of PFA-100 measurements performed on samples from healthy controls and from patients with von Willebrand disease or platelet disorders. It is shown that the PFA-100 system has a high sensitivity for von Willebrands disease, while the sensitivity for hereditary platelet dysfunction is low. In its present design this new device could not replace the template bleeding time as a screening test for primary hemostasis.</p>}},
author = {{Ridefelt, P and Egberg, N and Hillarp, A and Lethagen, S and Tengborn, L}},
issn = {{0023-7205}},
keywords = {{Bleeding Time/methods; Blood Platelet Disorders/blood; Hemostasis; Humans; Platelet Function Tests/instrumentation; Sensitivity and Specificity}},
language = {{swe}},
month = {{09}},
number = {{37}},
pages = {{4--3922}},
publisher = {{Swedish Medical Association}},
series = {{Lakartidningen}},
title = {{Ny in vitro-analys prövad: Blödningstid fortfarande bästa metod för test av den primära hemostasen}},
url = {{https://lakartidningen.se/wp-content/uploads/OldPdfFiles/2001/23402.pdf}},
volume = {{98}},
year = {{2001}},
}