Therapeutic Potential of Iridoid Derivatives: Patent Review.
(2019) In Inventions 4(2).- Abstract
- Iridoids belong to a family of monoterpenoids comprising the cyclopentan[c]-pyran system; this class of compounds offers a wide range of biological effects, namely antileishmanial, anticancer, antiplasmodial, and anti-inflammatory potency. To date, a large number of biologically active iridoid derivatives have been reported from various plant families, including Rubiaceae, Plantaginaceae, Scrophulariaceae, and Verbenaceae. Furthermore, iridoids have the potential to form conjugates with other anticancer, antidiabetic, antileishmanial, and antimalarial drugs which synergistically have the potential to increase their effects. Additionally, future research should focus on the synthesis of halo analogs as well as preparing homo dimers or... (More)
- Iridoids belong to a family of monoterpenoids comprising the cyclopentan[c]-pyran system; this class of compounds offers a wide range of biological effects, namely antileishmanial, anticancer, antiplasmodial, and anti-inflammatory potency. To date, a large number of biologically active iridoid derivatives have been reported from various plant families, including Rubiaceae, Plantaginaceae, Scrophulariaceae, and Verbenaceae. Furthermore, iridoids have the potential to form conjugates with other anticancer, antidiabetic, antileishmanial, and antimalarial drugs which synergistically have the potential to increase their effects. Additionally, future research should focus on the synthesis of halo analogs as well as preparing homo dimers or heterodimers of iridoids, since these might quite conceivably possess an increased bioactivity. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/9d45d58a-931d-40a7-93c2-dbe9f5a70288
- author
- Raza, Muhammad Liaquat LU ; Hussain, Hidayat ; Green, Ivan R. ; Saleem, Muhammad and Nazir, Mamona
- organization
- publishing date
- 2019
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Inventions
- volume
- 4
- issue
- 2
- article number
- 29
- publisher
- MDPI AG
- external identifiers
-
- scopus:85067894807
- ISSN
- 2411-5134
- DOI
- 10.3390/inventions4020029
- language
- English
- LU publication?
- yes
- id
- 9d45d58a-931d-40a7-93c2-dbe9f5a70288
- date added to LUP
- 2019-06-14 19:21:45
- date last changed
- 2022-04-26 01:35:20
@article{9d45d58a-931d-40a7-93c2-dbe9f5a70288,
abstract = {{Iridoids belong to a family of monoterpenoids comprising the cyclopentan[c]-pyran system; this class of compounds offers a wide range of biological effects, namely antileishmanial, anticancer, antiplasmodial, and anti-inflammatory potency. To date, a large number of biologically active iridoid derivatives have been reported from various plant families, including Rubiaceae, Plantaginaceae, Scrophulariaceae, and Verbenaceae. Furthermore, iridoids have the potential to form conjugates with other anticancer, antidiabetic, antileishmanial, and antimalarial drugs which synergistically have the potential to increase their effects. Additionally, future research should focus on the synthesis of halo analogs as well as preparing homo dimers or heterodimers of iridoids, since these might quite conceivably possess an increased bioactivity.}},
author = {{Raza, Muhammad Liaquat and Hussain, Hidayat and Green, Ivan R. and Saleem, Muhammad and Nazir, Mamona}},
issn = {{2411-5134}},
language = {{eng}},
number = {{2}},
publisher = {{MDPI AG}},
series = {{Inventions}},
title = {{Therapeutic Potential of Iridoid Derivatives: Patent Review.}},
url = {{http://dx.doi.org/10.3390/inventions4020029}},
doi = {{10.3390/inventions4020029}},
volume = {{4}},
year = {{2019}},
}