Computer simulation analysis of source-detector position for percutaneously measured O2-gas signal in a three-dimensional preterm infant lung
(2018) In Journal of Biophotonics 11(11).- Abstract
Further improvements in the clinical care of our most vulnerable patients-preterm infants-are needed. Novel diagnostic and surveillance tools facilitate such advances. The GASMAS technique has shown potential to become a tool to, noninvasively, monitor gas in the lungs of preterm infants, by placing a laser source and a detector on the chest wall skin. It is believed that this technology will become a valuable clinical diagnostic tool for monitoring the lung function of these patients. Today, the technology is, for this application, in an early stage and further investigations are needed. In the present study, a three-dimensional computer model of the thorax of an infant is constructed, from a set of CT images. Light transport... (More)
Further improvements in the clinical care of our most vulnerable patients-preterm infants-are needed. Novel diagnostic and surveillance tools facilitate such advances. The GASMAS technique has shown potential to become a tool to, noninvasively, monitor gas in the lungs of preterm infants, by placing a laser source and a detector on the chest wall skin. It is believed that this technology will become a valuable clinical diagnostic tool for monitoring the lung function of these patients. Today, the technology is, for this application, in an early stage and further investigations are needed. In the present study, a three-dimensional computer model of the thorax of an infant is constructed, from a set of CT images. Light transport simulations are performed to provide information about the position dependence of the laser- and detector probe on the thorax of the infant. The result of the simulations, based on the study method and the specified model used in this work, indicates that measurement geometries in front and on the side of the lung are favorable in order to obtain a good gas absorption signal.
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- author
- Liao, Peilang ; Larsson, Jim LU ; Krite Svanberg, Emilie LU ; Lundin, Patrik LU ; Swartling, Johannes ; Lewander Xu, Märta ; Bood, Joakim LU and Andersson-Engels, Stefan LU
- organization
- publishing date
- 2018-07-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Computational phantom, Light transport simulation, Preterm infants, Respiratory distress syndrome, Tunable diode laser absorption spectroscopy
- in
- Journal of Biophotonics
- volume
- 11
- issue
- 11
- article number
- e201800023
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- scopus:85050999982
- pmid:29978572
- ISSN
- 1864-063X
- DOI
- 10.1002/jbio.201800023
- language
- English
- LU publication?
- yes
- id
- b3a0ed98-4e89-4822-8cd3-6bf3f0b73449
- date added to LUP
- 2018-09-12 12:32:37
- date last changed
- 2024-05-13 14:30:30
@article{b3a0ed98-4e89-4822-8cd3-6bf3f0b73449,
abstract = {{<p>Further improvements in the clinical care of our most vulnerable patients-preterm infants-are needed. Novel diagnostic and surveillance tools facilitate such advances. The GASMAS technique has shown potential to become a tool to, noninvasively, monitor gas in the lungs of preterm infants, by placing a laser source and a detector on the chest wall skin. It is believed that this technology will become a valuable clinical diagnostic tool for monitoring the lung function of these patients. Today, the technology is, for this application, in an early stage and further investigations are needed. In the present study, a three-dimensional computer model of the thorax of an infant is constructed, from a set of CT images. Light transport simulations are performed to provide information about the position dependence of the laser- and detector probe on the thorax of the infant. The result of the simulations, based on the study method and the specified model used in this work, indicates that measurement geometries in front and on the side of the lung are favorable in order to obtain a good gas absorption signal.</p>}},
author = {{Liao, Peilang and Larsson, Jim and Krite Svanberg, Emilie and Lundin, Patrik and Swartling, Johannes and Lewander Xu, Märta and Bood, Joakim and Andersson-Engels, Stefan}},
issn = {{1864-063X}},
keywords = {{Computational phantom; Light transport simulation; Preterm infants; Respiratory distress syndrome; Tunable diode laser absorption spectroscopy}},
language = {{eng}},
month = {{07}},
number = {{11}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Journal of Biophotonics}},
title = {{Computer simulation analysis of source-detector position for percutaneously measured O<sub>2</sub>-gas signal in a three-dimensional preterm infant lung}},
url = {{http://dx.doi.org/10.1002/jbio.201800023}},
doi = {{10.1002/jbio.201800023}},
volume = {{11}},
year = {{2018}},
}