Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?
(2021) In Journal of Parkinson's Disease 11(3). p.909-917- Abstract
The use of stem cell derived dopamine neurons for treating patients with Parkinson's disease has now evolved to the first in human clinical trials. In this debate, we argue that assuming these trials give positive outcomes that this therapy will supercede DBS as the neurosurgical treatment of choice for PD patients in the future given it is a one-off therapy that repairs a critical pathway in the parkinsonian brain.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/bbdefa07-82ba-480c-b78c-119e769e9aa0
- author
- Barker, Roger A LU ; Björklund, Anders LU ; Frucht, Steven J and Svendsen, Clive N
- organization
- publishing date
- 2021-07-26
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Parkinson's Disease
- volume
- 11
- issue
- 3
- pages
- 9 pages
- publisher
- IOS Press
- external identifiers
-
- pmid:34334425
- scopus:85112139016
- ISSN
- 1877-718X
- DOI
- 10.3233/JPD-219008
- language
- English
- LU publication?
- yes
- id
- bbdefa07-82ba-480c-b78c-119e769e9aa0
- date added to LUP
- 2021-08-03 16:25:36
- date last changed
- 2024-07-27 18:14:09
@article{bbdefa07-82ba-480c-b78c-119e769e9aa0, abstract = {{<p>The use of stem cell derived dopamine neurons for treating patients with Parkinson's disease has now evolved to the first in human clinical trials. In this debate, we argue that assuming these trials give positive outcomes that this therapy will supercede DBS as the neurosurgical treatment of choice for PD patients in the future given it is a one-off therapy that repairs a critical pathway in the parkinsonian brain.</p>}}, author = {{Barker, Roger A and Björklund, Anders and Frucht, Steven J and Svendsen, Clive N}}, issn = {{1877-718X}}, language = {{eng}}, month = {{07}}, number = {{3}}, pages = {{909--917}}, publisher = {{IOS Press}}, series = {{Journal of Parkinson's Disease}}, title = {{Stem Derived Dopamine Neurons : Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?}}, url = {{http://dx.doi.org/10.3233/JPD-219008}}, doi = {{10.3233/JPD-219008}}, volume = {{11}}, year = {{2021}}, }