Regional motion correction for in vivo photoacoustic imaging in humans using interleaved ultrasound images
(2021) In Biomedical Optics Express 12(6). p.3312-3322- Abstract (Swedish)
- In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of... (More)
- In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of the controlled measurements show that the tracking corresponded to 97 ± 6% of the actual movement. Overall, the mean square error between PA images decreased by 52 ± 15% and by 43 ± 19% when correcting for controlled- and free-hand induced motions, respectively. The results show that the proposed algorithm could be used for motion correction in photoacoustic imaging in humans. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/c0723a59-9c1e-4be7-82ee-300af7b4dec4
- author
- Erlöv, Tobias LU ; Sheikh, Rafi LU ; Dahlstrand, Ulf LU ; Albinsson, John LU ; Malmsjö, Malin LU and Cinthio, Magnus LU
- organization
- publishing date
- 2021-05-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Image quality, In vivo imaging, Optical flow, Photoacoustic imaging, Spatial resolution, Spectral imaging
- in
- Biomedical Optics Express
- volume
- 12
- issue
- 6
- pages
- 11 pages
- publisher
- Optical Society of America
- external identifiers
-
- scopus:85105985644
- pmid:34221662
- ISSN
- 2156-7085
- DOI
- 10.1364/BOE.421644
- language
- Swedish
- LU publication?
- yes
- id
- c0723a59-9c1e-4be7-82ee-300af7b4dec4
- alternative location
- http://www.osapublishing.org/boe/abstract.cfm?URI=boe-12-6-3312
- date added to LUP
- 2021-05-17 14:57:05
- date last changed
- 2022-04-27 01:58:01
@article{c0723a59-9c1e-4be7-82ee-300af7b4dec4, abstract = {{In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of the controlled measurements show that the tracking corresponded to 97 ± 6% of the actual movement. Overall, the mean square error between PA images decreased by 52 ± 15% and by 43 ± 19% when correcting for controlled- and free-hand induced motions, respectively. The results show that the proposed algorithm could be used for motion correction in photoacoustic imaging in humans.}}, author = {{Erlöv, Tobias and Sheikh, Rafi and Dahlstrand, Ulf and Albinsson, John and Malmsjö, Malin and Cinthio, Magnus}}, issn = {{2156-7085}}, keywords = {{Image quality; In vivo imaging; Optical flow; Photoacoustic imaging; Spatial resolution; Spectral imaging}}, language = {{swe}}, month = {{05}}, number = {{6}}, pages = {{3312--3322}}, publisher = {{Optical Society of America}}, series = {{Biomedical Optics Express}}, title = {{Regional motion correction for in vivo photoacoustic imaging in humans using interleaved ultrasound images}}, url = {{http://dx.doi.org/10.1364/BOE.421644}}, doi = {{10.1364/BOE.421644}}, volume = {{12}}, year = {{2021}}, }