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Mapping of quantitative trait loci for lactation persistency traits in German Holstein dairy cattle

Harder, B. ; Bennewitz, J. ; Reinsch, N. ; Thaller, G. ; Thomsen, H. LU orcid ; Kühn, C. ; Schwerin, M. ; Erhardt, G. ; Förster, M. and Reinhardt, F. , et al. (2006) In Journal of Animal Breeding and Genetics 123(2). p.89-96
Abstract

A whole genome scan to map quantitative trait loci (QTL) for persistency of milk yield (PMY), persistency of fat yield (PFY), persistency of protein yield (PPY) and persistency of milk energy yield (PEY) was performed in a granddaughter design in the German Holstein dairy cattle population. The analysis included 16 paternal half-sib families with a total of 872 bulls. The analysis was carried out for the first lactation and for the first three lactations combined using univariate weighted multimarker regression. Controlling the false discovery rate across traits and data sets at a level of 0.15 and treating the four persistency traits as different traits revealed 27 significant QTL. A total of 12 chromosomes showed significant QTL... (More)

A whole genome scan to map quantitative trait loci (QTL) for persistency of milk yield (PMY), persistency of fat yield (PFY), persistency of protein yield (PPY) and persistency of milk energy yield (PEY) was performed in a granddaughter design in the German Holstein dairy cattle population. The analysis included 16 paternal half-sib families with a total of 872 bulls. The analysis was carried out for the first lactation and for the first three lactations combined using univariate weighted multimarker regression. Controlling the false discovery rate across traits and data sets at a level of 0.15 and treating the four persistency traits as different traits revealed 27 significant QTL. A total of 12 chromosomes showed significant QTL effects on a chromosomewise basis. The DGAT1 effect was highly significant for PPY and protein yield. A haplotype analysis using results of previous studies of the same design revealed a co-segregation of various persistency QTL and QTL affecting health traits like dystocia and stillbirth and functional traits like non-return rate 90 and somatic cell score.

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publishing date
type
Contribution to journal
publication status
published
in
Journal of Animal Breeding and Genetics
volume
123
issue
2
pages
89 - 96
publisher
Wiley-Blackwell
external identifiers
  • scopus:33644892507
  • pmid:16533362
ISSN
0931-2668
DOI
10.1111/j.1439-0388.2006.00577.x
language
English
LU publication?
no
id
cc9159e3-aae1-4deb-be1f-5c9a3e8e7150
date added to LUP
2018-10-10 13:34:10
date last changed
2025-06-25 05:49:37
@article{cc9159e3-aae1-4deb-be1f-5c9a3e8e7150,
  abstract     = {{<p>A whole genome scan to map quantitative trait loci (QTL) for persistency of milk yield (PMY), persistency of fat yield (PFY), persistency of protein yield (PPY) and persistency of milk energy yield (PEY) was performed in a granddaughter design in the German Holstein dairy cattle population. The analysis included 16 paternal half-sib families with a total of 872 bulls. The analysis was carried out for the first lactation and for the first three lactations combined using univariate weighted multimarker regression. Controlling the false discovery rate across traits and data sets at a level of 0.15 and treating the four persistency traits as different traits revealed 27 significant QTL. A total of 12 chromosomes showed significant QTL effects on a chromosomewise basis. The DGAT1 effect was highly significant for PPY and protein yield. A haplotype analysis using results of previous studies of the same design revealed a co-segregation of various persistency QTL and QTL affecting health traits like dystocia and stillbirth and functional traits like non-return rate 90 and somatic cell score.</p>}},
  author       = {{Harder, B. and Bennewitz, J. and Reinsch, N. and Thaller, G. and Thomsen, H. and Kühn, C. and Schwerin, M. and Erhardt, G. and Förster, M. and Reinhardt, F. and Kalm, E.}},
  issn         = {{0931-2668}},
  language     = {{eng}},
  month        = {{04}},
  number       = {{2}},
  pages        = {{89--96}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Journal of Animal Breeding and Genetics}},
  title        = {{Mapping of quantitative trait loci for lactation persistency traits in German Holstein dairy cattle}},
  url          = {{http://dx.doi.org/10.1111/j.1439-0388.2006.00577.x}},
  doi          = {{10.1111/j.1439-0388.2006.00577.x}},
  volume       = {{123}},
  year         = {{2006}},
}