RELATIONSHIP BETWEEN CYTOGENETIC FINDINGS AND HISTOPATHOLOGY IN NON‐HODGKIN LYMPHOMA
KRISTOFFERSSON, ULF LU ; HEIM, SVERRE LU ; OLSSON, HÅKAN LU
; ÅKERMAN, MÅNS
LU
and MITELMAN, FELIX
LU
(1987)
In Acta Pathologica Microbiologica Scandinavica. Section A. Pathology
95 A(1-6).
p.1-5
- Abstract
The cytogenetic findings in 70 patients with non‐Hodgkin lymphoma have been correlated with tumor histopathology according to the Kiel classification. Certain chromosome aberrations displayed a nonrandom association with the grade of malignancy: 4 lymphomas out of 6 with 1p+, 5 out of 7 with del(6)(q15), 7 out of 11 with 14q+, and 5 out of 8 with +18 belonged to the high grade malignancy group, whereas 9 lymphomas out of 10 with t(14;18) were low grade malignant. Two aberration types were closely associated with specific histopathologic subtypes: t(14; 18) occurred in 7 cases out of 10 in centroblastic/ centrocytic (cb/cc) follicular lymphomas, and 5 cases out of 6 with i(17q) were cb or cb/cc. Although less striking, there was a... (More)
The cytogenetic findings in 70 patients with non‐Hodgkin lymphoma have been correlated with tumor histopathology according to the Kiel classification. Certain chromosome aberrations displayed a nonrandom association with the grade of malignancy: 4 lymphomas out of 6 with 1p+, 5 out of 7 with del(6)(q15), 7 out of 11 with 14q+, and 5 out of 8 with +18 belonged to the high grade malignancy group, whereas 9 lymphomas out of 10 with t(14;18) were low grade malignant. Two aberration types were closely associated with specific histopathologic subtypes: t(14; 18) occurred in 7 cases out of 10 in centroblastic/ centrocytic (cb/cc) follicular lymphomas, and 5 cases out of 6 with i(17q) were cb or cb/cc. Although less striking, there was a tendency for del(6)(q15) to occur in cb or cb/cc lymphomas (4 cases out of 7), in contrast to only 1 case out of 5 with the more distal deletion del(6)(q21).
(Less)
- author
- KRISTOFFERSSON, ULF
LU
; HEIM, SVERRE
LU
; OLSSON, HÅKAN
LU
; ÅKERMAN, MÅNS
LU
and MITELMAN, FELIX
LU
- organization
- publishing date
- 1987-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cytogenetic correlations, Kiel‐classification, Non‐Hodgkin lymphoma
- in
- Acta Pathologica Microbiologica Scandinavica. Section A. Pathology
- volume
- 95 A
- issue
- 1-6
- pages
- 1 - 5
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:3825539
- scopus:0023147712
- ISSN
- 0108-0164
- DOI
- 10.1111/j.1699-0463.1987.tb00001_95A.x
- language
- English
- LU publication?
- yes
- id
- cf274940-f2e8-4752-970d-b1e602fda9f1
- date added to LUP
- 2018-12-17 16:46:56
- date last changed
- 2024-01-15 10:05:58
@article{cf274940-f2e8-4752-970d-b1e602fda9f1,
abstract = {{<p>The cytogenetic findings in 70 patients with non‐Hodgkin lymphoma have been correlated with tumor histopathology according to the Kiel classification. Certain chromosome aberrations displayed a nonrandom association with the grade of malignancy: 4 lymphomas out of 6 with 1p+, 5 out of 7 with del(6)(q15), 7 out of 11 with 14q+, and 5 out of 8 with +18 belonged to the high grade malignancy group, whereas 9 lymphomas out of 10 with t(14;18) were low grade malignant. Two aberration types were closely associated with specific histopathologic subtypes: t(14; 18) occurred in 7 cases out of 10 in centroblastic/ centrocytic (cb/cc) follicular lymphomas, and 5 cases out of 6 with i(17q) were cb or cb/cc. Although less striking, there was a tendency for del(6)(q15) to occur in cb or cb/cc lymphomas (4 cases out of 7), in contrast to only 1 case out of 5 with the more distal deletion del(6)(q21).</p>}},
author = {{KRISTOFFERSSON, ULF and HEIM, SVERRE and OLSSON, HÅKAN and ÅKERMAN, MÅNS and MITELMAN, FELIX}},
issn = {{0108-0164}},
keywords = {{cytogenetic correlations; Kiel‐classification; Non‐Hodgkin lymphoma}},
language = {{eng}},
month = {{01}},
number = {{1-6}},
pages = {{1--5}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Acta Pathologica Microbiologica Scandinavica. Section A. Pathology}},
title = {{RELATIONSHIP BETWEEN CYTOGENETIC FINDINGS AND HISTOPATHOLOGY IN NON‐HODGKIN LYMPHOMA}},
url = {{http://dx.doi.org/10.1111/j.1699-0463.1987.tb00001_95A.x}},
doi = {{10.1111/j.1699-0463.1987.tb00001_95A.x}},
volume = {{95 A}},
year = {{1987}},
}