Muscle mass, creatinine, cystatin C, and selective glomerular hypofiltration syndromes
(2023) In Clinical Kidney Journal- Abstract
- In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation of glomerular filtration rate (GFR) by use of creatinine and a measure, total lumbar muscle cross-sectional area, reflecting the total muscle mass of an individual, is superior to GFRestimating equations based upon creatinine and demographic variables. The report by Stehlé et al demonstrates one solution to the interference of muscle mass in the use of creatinine to estimate GFR. This interference was identified already at the start in 1959 of using creatinine for estimation of GFR. Different ways of taking the muscle mass into account when creatinine-based estimations of GFR have been used generally include use of controversial race and sex... (More)
- In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation of glomerular filtration rate (GFR) by use of creatinine and a measure, total lumbar muscle cross-sectional area, reflecting the total muscle mass of an individual, is superior to GFRestimating equations based upon creatinine and demographic variables. The report by Stehlé et al demonstrates one solution to the interference of muscle mass in the use of creatinine to estimate GFR. This interference was identified already at the start in 1959 of using creatinine for estimation of GFR. Different ways of taking the muscle mass into account when creatinine-based estimations of GFR have been used generally include use of controversial race and sex coefficients. A new marker of GFR, cystatin C, introduced in 1979, has been shown to be virtually uninfluenced by muscle mass. In this editorial, the simultaneous use of creatinine and cystatin C to estimate GFR, muscle mass and selective glomerular hypofiltration syndromes is described. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d12d22b7-ac46-4b97-b400-90cae5c97491
- author
- Malmgren, Linnea LU and Grubb, Anders LU
- organization
- publishing date
- 2023-04
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cystatin C, creatinine, GFR,, selective glomerular hypofiltration
- in
- Clinical Kidney Journal
- publisher
- Oxford University Press
- external identifiers
-
- pmid:37529657
- scopus:85173235570
- ISSN
- 2048-8505
- DOI
- 10.1093/ckj/sfad086
- language
- English
- LU publication?
- yes
- id
- d12d22b7-ac46-4b97-b400-90cae5c97491
- date added to LUP
- 2023-04-23 14:39:47
- date last changed
- 2024-07-28 04:01:50
@article{d12d22b7-ac46-4b97-b400-90cae5c97491, abstract = {{In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation of glomerular filtration rate (GFR) by use of creatinine and a measure, total lumbar muscle cross-sectional area, reflecting the total muscle mass of an individual, is superior to GFRestimating equations based upon creatinine and demographic variables. The report by Stehlé et al demonstrates one solution to the interference of muscle mass in the use of creatinine to estimate GFR. This interference was identified already at the start in 1959 of using creatinine for estimation of GFR. Different ways of taking the muscle mass into account when creatinine-based estimations of GFR have been used generally include use of controversial race and sex coefficients. A new marker of GFR, cystatin C, introduced in 1979, has been shown to be virtually uninfluenced by muscle mass. In this editorial, the simultaneous use of creatinine and cystatin C to estimate GFR, muscle mass and selective glomerular hypofiltration syndromes is described.}}, author = {{Malmgren, Linnea and Grubb, Anders}}, issn = {{2048-8505}}, keywords = {{cystatin C, creatinine, GFR,; selective glomerular hypofiltration}}, language = {{eng}}, publisher = {{Oxford University Press}}, series = {{Clinical Kidney Journal}}, title = {{Muscle mass, creatinine, cystatin C, and selective glomerular hypofiltration syndromes}}, url = {{http://dx.doi.org/10.1093/ckj/sfad086}}, doi = {{10.1093/ckj/sfad086}}, year = {{2023}}, }