The yield of screening symptomatic contacts of multidrug-resistant tuberculosis cases at a tertiary hospital in Addis Ababa, Ethiopia.
(2015) In BMC Research Notes 8. p.1-6- Abstract
- Background
Early detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethiopia. Here we present our findings on the extent of screening symptomatic contacts and its yield in a tertiary hospital in a major urban setting in Ethiopia.
Results
Symptomatic household contacts were identified in 29 (5.7 %) of 508 index cases treated at the hospital. There were a total of 155 family members in the households traced... (More) - Background
Early detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethiopia. Here we present our findings on the extent of screening symptomatic contacts and its yield in a tertiary hospital in a major urban setting in Ethiopia.
Results
Symptomatic household contacts were identified in 29 (5.7 %) of 508 index cases treated at the hospital. There were a total of 155 family members in the households traced of whom 16 (10 %) had confirmed MDR-TB. At least one confirmed MDR-TB cases was identified in 15 (51.7 %) of the 29 traced households.
Conclusions
Tracing symptomatic contacts of MDR-TB cases could be a high yield strategy for early detection and treatment of MDR-TB cases in the community. The approach should be promoted for wider adoption and dissemination. Larger scale studies should be done to determine its effectiveness and sustainability in similar settings.
(Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d51f3c14-6359-47b4-9720-f2e1246a54f3
- author
- Titiyos, A ; Jerene, Degu LU and Enquselassie, F
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- in
- BMC Research Notes
- volume
- 8
- article number
- 501
- pages
- 1 - 6
- publisher
- BioMed Central (BMC)
- external identifiers
-
- scopus:84942802076
- ISSN
- 1756-0500
- DOI
- 10.1186/s13104-015-1442-z
- project
- LUC3 - Lund University Child Centered Care
- language
- English
- LU publication?
- no
- id
- d51f3c14-6359-47b4-9720-f2e1246a54f3
- date added to LUP
- 2019-06-28 10:55:16
- date last changed
- 2022-03-10 18:25:02
@article{d51f3c14-6359-47b4-9720-f2e1246a54f3, abstract = {{Background<br/>Early detection and treatment of multidrug-resistant tuberculosis (MDR-TB, resistant to isoniazid and rifampicin) is an urgent global priority. Identifying and tracing close contacts of patients with MDR-TB could be a feasible strategy to achieve this goal. However, there is limited experience with contact tracing among patients with drug-resistant tuberculosis both globally and in Ethiopia. Here we present our findings on the extent of screening symptomatic contacts and its yield in a tertiary hospital in a major urban setting in Ethiopia.<br/>Results<br/>Symptomatic household contacts were identified in 29 (5.7 %) of 508 index cases treated at the hospital. There were a total of 155 family members in the households traced of whom 16 (10 %) had confirmed MDR-TB. At least one confirmed MDR-TB cases was identified in 15 (51.7 %) of the 29 traced households.<br/>Conclusions<br/>Tracing symptomatic contacts of MDR-TB cases could be a high yield strategy for early detection and treatment of MDR-TB cases in the community. The approach should be promoted for wider adoption and dissemination. Larger scale studies should be done to determine its effectiveness and sustainability in similar settings.<br/>}}, author = {{Titiyos, A and Jerene, Degu and Enquselassie, F}}, issn = {{1756-0500}}, language = {{eng}}, pages = {{1--6}}, publisher = {{BioMed Central (BMC)}}, series = {{BMC Research Notes}}, title = {{The yield of screening symptomatic contacts of multidrug-resistant tuberculosis cases at a tertiary hospital in Addis Ababa, Ethiopia.}}, url = {{http://dx.doi.org/10.1186/s13104-015-1442-z}}, doi = {{10.1186/s13104-015-1442-z}}, volume = {{8}}, year = {{2015}}, }