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Bone health as a co-morbidity of chronic kidney disease

Malmgren, Linnea LU orcid and Mcguigan, Fiona LU orcid (2022) In Best Practice and Research: Clinical Rheumatology 36(3).
Abstract
Chronic kidney disease and osteoporosis commonly co-exist in aged patients. Chronic kidney disease affects bone health because of its effect on mineral metabolism in the syndrome, Chronic Kidney Disease Mineral and Bone Disorder, resulting in an increased risk of fractures. Hip fracture risk may be as much as four-fold higher in the worst affected. Tools to estimate fracture risk such as FRAX® and measuring bone density can be used in patients with chronic kidney disease; however, bone density may underestimate fracture risk in this population as it does not give information on bone quality. While osteoporosis treatment in patients with chronic kidney disease stage 1–3 does not differ from the general population, in the absence of Chronic... (More)
Chronic kidney disease and osteoporosis commonly co-exist in aged patients. Chronic kidney disease affects bone health because of its effect on mineral metabolism in the syndrome, Chronic Kidney Disease Mineral and Bone Disorder, resulting in an increased risk of fractures. Hip fracture risk may be as much as four-fold higher in the worst affected. Tools to estimate fracture risk such as FRAX® and measuring bone density can be used in patients with chronic kidney disease; however, bone density may underestimate fracture risk in this population as it does not give information on bone quality. While osteoporosis treatment in patients with chronic kidney disease stage 1–3 does not differ from the general population, in the absence of Chronic Kidney Disease Mineral and Bone Disorder, patients with disease stage 4–5 require special consideration. It is, however, of the utmost importance that these patients receive pharmacological treatment because of their high risk of fractures. (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Best Practice and Research: Clinical Rheumatology
volume
36
issue
3
article number
101760
publisher
Elsevier
external identifiers
  • scopus:85132511887
  • pmid:35718689
ISSN
1521-6942
DOI
10.1016/j.berh.2022.101760
language
English
LU publication?
yes
id
de4272dc-0629-42f3-b190-61f07a106a17
date added to LUP
2022-06-17 09:33:04
date last changed
2024-05-27 16:17:29
@article{de4272dc-0629-42f3-b190-61f07a106a17,
  abstract     = {{Chronic kidney disease and osteoporosis commonly co-exist in aged patients. Chronic kidney disease affects bone health because of its effect on mineral metabolism in the syndrome, Chronic Kidney Disease Mineral and Bone Disorder, resulting in an increased risk of fractures. Hip fracture risk may be as much as four-fold higher in the worst affected. Tools to estimate fracture risk such as FRAX® and measuring bone density can be used in patients with chronic kidney disease; however, bone density may underestimate fracture risk in this population as it does not give information on bone quality. While osteoporosis treatment in patients with chronic kidney disease stage 1–3 does not differ from the general population, in the absence of Chronic Kidney Disease Mineral and Bone Disorder, patients with disease stage 4–5 require special consideration. It is, however, of the utmost importance that these patients receive pharmacological treatment because of their high risk of fractures.}},
  author       = {{Malmgren, Linnea and Mcguigan, Fiona}},
  issn         = {{1521-6942}},
  language     = {{eng}},
  number       = {{3}},
  publisher    = {{Elsevier}},
  series       = {{Best Practice and Research: Clinical Rheumatology}},
  title        = {{Bone health as a co-morbidity of chronic kidney disease}},
  url          = {{http://dx.doi.org/10.1016/j.berh.2022.101760}},
  doi          = {{10.1016/j.berh.2022.101760}},
  volume       = {{36}},
  year         = {{2022}},
}