Associations between Divorce and Onset of Drug Abuse in a Swedish National Sample
(2018) In American Journal of Epidemiology 187(5). p.1010-1018- Abstract
Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-Abuse onset. In models with adjustments, divorce was associated with a substantial increase in... (More)
Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-Abuse onset. In models with adjustments, divorce was associated with a substantial increase in risk of drug-Abuse onset in both sexes (hazard ratios > 5). Co-relative analyses (among biological relatives) were consistent with a partially causal role of divorce on drug-Abuse onset. Widowhood also increased risk of drug-Abuse onset, although to a lesser extent. Divorce is a potent risk factor for onset of drug abuse, even after adjusting for deviant behavior in adolescence and family history of drug abuse. The somewhat less-pronounced association with widowhood, particularly among men, suggests that the magnitude of association between divorce and drug abuse may not be generalizable to the end of a relationship.
(Less)
- author
- Edwards, Alexis C. ; Larsson Lönn, Sara LU ; Sundquist, Jan LU ; Kendler, Kenneth S. and Sundquist, Kristina LU
- organization
- publishing date
- 2018-05-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- addiction, divorce, drug abuse, family history, widowhood
- in
- American Journal of Epidemiology
- volume
- 187
- issue
- 5
- pages
- 9 pages
- publisher
- Oxford University Press
- external identifiers
-
- scopus:85047130147
- pmid:29155917
- ISSN
- 0002-9262
- DOI
- 10.1093/aje/kwx321
- language
- English
- LU publication?
- yes
- id
- e0377490-f3b5-41c7-ba89-2f12a892871d
- date added to LUP
- 2018-10-29 09:31:40
- date last changed
- 2024-04-15 16:24:13
@article{e0377490-f3b5-41c7-ba89-2f12a892871d,
abstract = {{<p>Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-Abuse onset. In models with adjustments, divorce was associated with a substantial increase in risk of drug-Abuse onset in both sexes (hazard ratios > 5). Co-relative analyses (among biological relatives) were consistent with a partially causal role of divorce on drug-Abuse onset. Widowhood also increased risk of drug-Abuse onset, although to a lesser extent. Divorce is a potent risk factor for onset of drug abuse, even after adjusting for deviant behavior in adolescence and family history of drug abuse. The somewhat less-pronounced association with widowhood, particularly among men, suggests that the magnitude of association between divorce and drug abuse may not be generalizable to the end of a relationship.</p>}},
author = {{Edwards, Alexis C. and Larsson Lönn, Sara and Sundquist, Jan and Kendler, Kenneth S. and Sundquist, Kristina}},
issn = {{0002-9262}},
keywords = {{addiction; divorce; drug abuse; family history; widowhood}},
language = {{eng}},
month = {{05}},
number = {{5}},
pages = {{1010--1018}},
publisher = {{Oxford University Press}},
series = {{American Journal of Epidemiology}},
title = {{Associations between Divorce and Onset of Drug Abuse in a Swedish National Sample}},
url = {{http://dx.doi.org/10.1093/aje/kwx321}},
doi = {{10.1093/aje/kwx321}},
volume = {{187}},
year = {{2018}},
}