SiPP (Stroke in Pregnancy and Postpartum) : A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women
(2020) In European Stroke Journal 5(2). p.193-203- Abstract
Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn. Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients, their predictors and infant outcome. Methods and design: This is an observational, prospective, multicentre, international case–control study. The study will include patients with cerebrovascular events during... (More)
Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn. Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients, their predictors and infant outcome. Methods and design: This is an observational, prospective, multicentre, international case–control study. The study will include patients with cerebrovascular events during pregnancy and/or within six months after delivery. For each included case, two controls will be prospectively recruited: one pregnant or puerperal subject without any history of cerebrovascular event and one non-pregnant or non-puerperal subject with a recent cerebrovascular event. All controls will be matched by age, ethnicity and type of cerebrovascular event with their assigned cases. The pregnant controls will be matched also by pregnancy weeks/trimester. Follow-up will last 24 months for the mother and 12 months for the infant. Summary: To better understand causes and outcomes of uncommon conditions like pregnancy/postpartum-related cerebrovascular events, the development of multisite, multidisciplinary registry-based studies, such as the Stroke in Pregnancy and Postpartum study, is needed in order to collect an adequate number of patients, draw reliable conclusions and give definite recommendations on their management.
(Less)
- author
- author collaboration
- organization
- publishing date
- 2020-06-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cerebrovascular disease, outcome, postpartum, pregnancy, puerperium, Stroke
- in
- European Stroke Journal
- volume
- 5
- issue
- 2
- pages
- 11 pages
- publisher
- SAGE Publications
- external identifiers
-
- pmid:32637653
- scopus:85077375173
- ISSN
- 2396-9873
- DOI
- 10.1177/2396987319893512
- project
- Stroke under graviditet och efter förlossning
- language
- English
- LU publication?
- yes
- id
- e4fd9f5e-bbfe-48ea-997d-11f7260b408f
- date added to LUP
- 2020-01-17 13:36:36
- date last changed
- 2024-04-03 00:26:21
@article{e4fd9f5e-bbfe-48ea-997d-11f7260b408f,
abstract = {{<p>Rationale: Cerebrovascular diseases associated with pregnancy and postpartum period are uncommon; however, they can have an important impact on health of both women and foetus or newborn. Aims: To evaluate the frequency, characteristics and management of cerebrovascular events in pregnant/postpartum women, to clarify pathophysiological mechanisms underlying the occurrence of these events including biomolecular aspects, and to assess the short- and long-term cerebrovascular and global cardiovascular outcome of these patients, their predictors and infant outcome. Methods and design: This is an observational, prospective, multicentre, international case–control study. The study will include patients with cerebrovascular events during pregnancy and/or within six months after delivery. For each included case, two controls will be prospectively recruited: one pregnant or puerperal subject without any history of cerebrovascular event and one non-pregnant or non-puerperal subject with a recent cerebrovascular event. All controls will be matched by age, ethnicity and type of cerebrovascular event with their assigned cases. The pregnant controls will be matched also by pregnancy weeks/trimester. Follow-up will last 24 months for the mother and 12 months for the infant. Summary: To better understand causes and outcomes of uncommon conditions like pregnancy/postpartum-related cerebrovascular events, the development of multisite, multidisciplinary registry-based studies, such as the Stroke in Pregnancy and Postpartum study, is needed in order to collect an adequate number of patients, draw reliable conclusions and give definite recommendations on their management.</p>}},
author = {{Lorenzano, Svetlana and Kremer, Christine and Pavlovic, Aleksandra and Jovanovic, Dejana R. and Sandset, Else Charlotte and Christensen, Hanne and Bushnell, Cheryl and Arsovska, Anita and Sprigg, Nikola and Roffe, Christine and Ijäs, Petra and Gdovinova, Zuzana and Alexandrov, Anne and Zedde, Marialuisa and Tassi, Rossana and Acciaresi, Monica and Lantz, Maria and Sunnerhagen, Katharina and Zarkov, Marija and Rantanen, Kirsi and Perren, Fabienne and Iversen, Helle K. and Kruuse, Christina and Slowik, Agnieszka and Palazzo, Paola and Korv, Janika and Fromm, Annette and Lovrencic-Huzjan, Arijana and Korompoki, Eleni and Fonseca, Ana Catarina and Gall, Seana L. and Brunner, Freimuth and Caso, Valeria and Sacco, Simona}},
issn = {{2396-9873}},
keywords = {{cerebrovascular disease; outcome; postpartum; pregnancy; puerperium; Stroke}},
language = {{eng}},
month = {{06}},
number = {{2}},
pages = {{193--203}},
publisher = {{SAGE Publications}},
series = {{European Stroke Journal}},
title = {{SiPP (Stroke in Pregnancy and Postpartum) : A prospective, observational, international, multicentre study on pathophysiological mechanisms, clinical profile, management and outcome of cerebrovascular diseases in pregnant and postpartum women}},
url = {{http://dx.doi.org/10.1177/2396987319893512}},
doi = {{10.1177/2396987319893512}},
volume = {{5}},
year = {{2020}},
}