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Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease

Dalman-Skogby, Sandra ; Bay, Annika ; Christersson, Christina ; Hlebowicz, Joanna LU ; Mandalenakis, Zacharias ; Goossens, Eva ; Kovacs, Adrienne H. ; Van Bulck, Liesbet ; Luyckx, Koen and Moons, Philip , et al. (2026) In International Journal of Cardiology Congenital Heart Disease 24.
Abstract

Structured Abstract Background Sexual health and functioning are significant, yet often overlooked, components of psychosocial well-being of adults with congenital heart disease (ACHD). Prior research reports inconsistent findings, limited data on older adults with CHD, and few studies have compared patients with controls from the general population. This study investigated sexual functioning in middle-aged and elderly ACHD patients and compared it with controls. Methods This was a Swedish sub-study of the international APPROACH-IS II project. Patients 40 years or older with moderate or severe CHD were recruited, along with controls from the general Swedish population. The design was case control. Erectile dysfunction (ED) in males was... (More)

Structured Abstract Background Sexual health and functioning are significant, yet often overlooked, components of psychosocial well-being of adults with congenital heart disease (ACHD). Prior research reports inconsistent findings, limited data on older adults with CHD, and few studies have compared patients with controls from the general population. This study investigated sexual functioning in middle-aged and elderly ACHD patients and compared it with controls. Methods This was a Swedish sub-study of the international APPROACH-IS II project. Patients 40 years or older with moderate or severe CHD were recruited, along with controls from the general Swedish population. The design was case control. Erectile dysfunction (ED) in males was assessed using the International Index of Erectile Function. Sexual dysfunction (SD) in females was assessed using the Female Sexual Function Index. Results Overall, 146 individuals were included in the study; 90 patients with CHD and 56 controls. Among males, the prevalence of ED was higher in patients (n = 57) than in controls (n = 37), (21% vs. 2.7%, p = 0.01). ED was associated with increasing age (OR = 1.11; 95% CI 1.03-1.20). Among females, no difference in the prevalence of SD was observed between patients (n = 33) and controls (n = 19) (27% vs. 30%, p = 0.76) Conclusion Sexual dysfunction was more common in male patients than controls, whereas no differences were observed between female patients and controls. Given that approximately one in five males and one in four females with CHD reported sexual dysfunction, increased empirical and clinical attention is warranted.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aging, Congenital, Dysfunction, Erectile, Heart defects, Physiological, Sexual dysfunction, Sexual health
in
International Journal of Cardiology Congenital Heart Disease
volume
24
article number
100664
publisher
Elsevier
external identifiers
  • scopus:105032543059
  • pmid:41869685
ISSN
2666-6685
DOI
10.1016/j.ijcchd.2026.100664
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2026 The Authors.
id
ee534e07-b528-496e-9a2b-5c9162948d4e
date added to LUP
2026-05-18 13:26:12
date last changed
2026-05-19 03:00:02
@article{ee534e07-b528-496e-9a2b-5c9162948d4e,
  abstract     = {{<p>Structured Abstract Background Sexual health and functioning are significant, yet often overlooked, components of psychosocial well-being of adults with congenital heart disease (ACHD). Prior research reports inconsistent findings, limited data on older adults with CHD, and few studies have compared patients with controls from the general population. This study investigated sexual functioning in middle-aged and elderly ACHD patients and compared it with controls. Methods This was a Swedish sub-study of the international APPROACH-IS II project. Patients 40 years or older with moderate or severe CHD were recruited, along with controls from the general Swedish population. The design was case control. Erectile dysfunction (ED) in males was assessed using the International Index of Erectile Function. Sexual dysfunction (SD) in females was assessed using the Female Sexual Function Index. Results Overall, 146 individuals were included in the study; 90 patients with CHD and 56 controls. Among males, the prevalence of ED was higher in patients (n = 57) than in controls (n = 37), (21% vs. 2.7%, p = 0.01). ED was associated with increasing age (OR = 1.11; 95% CI 1.03-1.20). Among females, no difference in the prevalence of SD was observed between patients (n = 33) and controls (n = 19) (27% vs. 30%, p = 0.76) Conclusion Sexual dysfunction was more common in male patients than controls, whereas no differences were observed between female patients and controls. Given that approximately one in five males and one in four females with CHD reported sexual dysfunction, increased empirical and clinical attention is warranted.</p>}},
  author       = {{Dalman-Skogby, Sandra and Bay, Annika and Christersson, Christina and Hlebowicz, Joanna and Mandalenakis, Zacharias and Goossens, Eva and Kovacs, Adrienne H. and Van Bulck, Liesbet and Luyckx, Koen and Moons, Philip and Sandberg, Camilla and Johansson, Bengt}},
  issn         = {{2666-6685}},
  keywords     = {{Aging; Congenital; Dysfunction; Erectile; Heart defects; Physiological; Sexual dysfunction; Sexual health}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{International Journal of Cardiology Congenital Heart Disease}},
  title        = {{Sexual functioning after the age of 40 in adults with moderate or severe congenital heart disease}},
  url          = {{http://dx.doi.org/10.1016/j.ijcchd.2026.100664}},
  doi          = {{10.1016/j.ijcchd.2026.100664}},
  volume       = {{24}},
  year         = {{2026}},
}