Autoimmune Type 1 Diabetes
Akel, Omar LU
and Lernmark, Åke
LU
(2024)
p.203-215
- Abstract
In this chapter, the authors summarize the current knowledge of possible trigger(s) of p-cell autoimmunity and factors affecting the progression to the clinical onset in individuals who have developed one or more p-cell autoantibodies. Testing islet autoantibodies at random or in select populations such as schoolchildren should inform about the epidemiology of autoimmune islet disease and what to expect in the years to come about the epidemiology of autoimmune type 1 diabetes. The aetiology and pathogenesis are better understood, especially as the aetiology can be better defined in terms of genetic and environmental aetiology and that the cause and origin of autoimmune type 1 diabetes are beginning to be understood. Islet autoantibodies... (More)
In this chapter, the authors summarize the current knowledge of possible trigger(s) of p-cell autoimmunity and factors affecting the progression to the clinical onset in individuals who have developed one or more p-cell autoantibodies. Testing islet autoantibodies at random or in select populations such as schoolchildren should inform about the epidemiology of autoimmune islet disease and what to expect in the years to come about the epidemiology of autoimmune type 1 diabetes. The aetiology and pathogenesis are better understood, especially as the aetiology can be better defined in terms of genetic and environmental aetiology and that the cause and origin of autoimmune type 1 diabetes are beginning to be understood. Islet autoantibodies have been studied longitudinally in a large number of first-degree relatives of people with type 1 diabetes until the clinical onset of type 1 diabetes.
(Less)
- author
- Akel, Omar
LU
and Lernmark, Åke
LU
- organization
- publishing date
- 2024-01-01
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- autoimmune type 1 diabetes, cellular autoimmunity, diabetes diagnosis, epidemiology, genetic aetiology, islet autoimmunity, pathogenesis, virus aetiology
- host publication
- Textbook of Diabetes
- editor
- Holt, Richard IG and Flyvbjerg, Allan
- edition
- Sixth edition
- pages
- 203 - 215
- publisher
- Wiley
- external identifiers
-
- scopus:105006538517
- ISBN
- 9781119697473
- 9781119697428
- DOI
- 10.1002/9781119697473.ch14
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2024 John Wiley & Sons Ltd.
- id
- fbbbe81d-5e82-4f8d-b050-abc32f7315bc
- date added to LUP
- 2025-06-12 14:15:31
- date last changed
- 2025-07-10 17:12:20
@inbook{fbbbe81d-5e82-4f8d-b050-abc32f7315bc,
abstract = {{<p>In this chapter, the authors summarize the current knowledge of possible trigger(s) of p-cell autoimmunity and factors affecting the progression to the clinical onset in individuals who have developed one or more p-cell autoantibodies. Testing islet autoantibodies at random or in select populations such as schoolchildren should inform about the epidemiology of autoimmune islet disease and what to expect in the years to come about the epidemiology of autoimmune type 1 diabetes. The aetiology and pathogenesis are better understood, especially as the aetiology can be better defined in terms of genetic and environmental aetiology and that the cause and origin of autoimmune type 1 diabetes are beginning to be understood. Islet autoantibodies have been studied longitudinally in a large number of first-degree relatives of people with type 1 diabetes until the clinical onset of type 1 diabetes.</p>}},
author = {{Akel, Omar and Lernmark, Åke}},
booktitle = {{Textbook of Diabetes}},
editor = {{Holt, Richard IG and Flyvbjerg, Allan}},
isbn = {{9781119697473}},
keywords = {{autoimmune type 1 diabetes; cellular autoimmunity; diabetes diagnosis; epidemiology; genetic aetiology; islet autoimmunity; pathogenesis; virus aetiology}},
language = {{eng}},
month = {{01}},
pages = {{203--215}},
publisher = {{Wiley}},
title = {{Autoimmune Type 1 Diabetes}},
url = {{http://dx.doi.org/10.1002/9781119697473.ch14}},
doi = {{10.1002/9781119697473.ch14}},
year = {{2024}},
}