Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design
(2014) In Journal of Materials Chemistry. B 46. p.8053-8068- Abstract
The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/fc6af738-3c1d-4b12-b812-5e58cfcaa04f
- author
- Jones, Charles H ; Hakansson, Anders P LU and Pfeifer, Blaine A
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- in
- Journal of Materials Chemistry. B
- volume
- 46
- pages
- 8053 - 8068
- publisher
- Royal Society of Chemistry
- external identifiers
-
- scopus:84908577903
- pmid:29887986
- ISSN
- 2050-750X
- DOI
- 10.1039/C4TB01058B
- language
- English
- LU publication?
- no
- id
- fc6af738-3c1d-4b12-b812-5e58cfcaa04f
- date added to LUP
- 2018-09-21 13:37:19
- date last changed
- 2024-10-15 07:23:16
@article{fc6af738-3c1d-4b12-b812-5e58cfcaa04f, abstract = {{<p>The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.</p>}}, author = {{Jones, Charles H and Hakansson, Anders P and Pfeifer, Blaine A}}, issn = {{2050-750X}}, language = {{eng}}, pages = {{8053--8068}}, publisher = {{Royal Society of Chemistry}}, series = {{Journal of Materials Chemistry. B}}, title = {{Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design}}, url = {{http://dx.doi.org/10.1039/C4TB01058B}}, doi = {{10.1039/C4TB01058B}}, volume = {{46}}, year = {{2014}}, }