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Identifying carriers at high risk for negative reactions when performing prenatal diagnosis of haemophilia

Tedgård, U. LU ; Ljung, R. LU orcid ; Mcneil, T.F. LU and Landegren Tedgård, Eva LU (1997) In Haemophilia 3(2). p.123-130
Abstract
The aim of the current study was to determine which pregnant carriers of haemophilia are at particularly high risk for having notably negative psychological reactions in association with prenatal diagnosis (PND) by fetal blood sampling of offspring haemophilia. Among 29 carriers of haemophilia A or B, notable psychiatric or psychosomatic symptoms in association with PND were significantly related to the woman's having a negative view of herself in general and of being a gene carrier, a planned pregnancy, high education, a good general knowledge of haemophilia and a guiding philosophy of life. Women with strong negative reactions significantly more often reported signs of depressive mood at follow-up. The results suggest that giving more... (More)
The aim of the current study was to determine which pregnant carriers of haemophilia are at particularly high risk for having notably negative psychological reactions in association with prenatal diagnosis (PND) by fetal blood sampling of offspring haemophilia. Among 29 carriers of haemophilia A or B, notable psychiatric or psychosomatic symptoms in association with PND were significantly related to the woman's having a negative view of herself in general and of being a gene carrier, a planned pregnancy, high education, a good general knowledge of haemophilia and a guiding philosophy of life. Women with strong negative reactions significantly more often reported signs of depressive mood at follow-up. The results suggest that giving more information and promoting increased knowledge about the disease and the PND procedure will, by itself, not help women to cope better emotionally. Provision of prospective psychosocial support is recommended. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
keywords
article, clinical article, depression, disease carrier, fetus, fetus blood, hemophilia A, hemophilia B, human, mood, prenatal diagnosis, priority journal
in
Haemophilia
volume
3
issue
2
pages
123 - 130
publisher
Wiley-Blackwell
external identifiers
  • scopus:0030902308
ISSN
1351-8216
DOI
10.1046/j.1365-2516.1997.00093.x
language
English
LU publication?
yes
id
fdd3d790-5d7f-4afb-a551-970acc475922
date added to LUP
2016-11-25 14:23:24
date last changed
2022-09-07 22:13:22
@article{fdd3d790-5d7f-4afb-a551-970acc475922,
  abstract     = {{The aim of the current study was to determine which pregnant carriers of haemophilia are at particularly high risk for having notably negative psychological reactions in association with prenatal diagnosis (PND) by fetal blood sampling of offspring haemophilia. Among 29 carriers of haemophilia A or B, notable psychiatric or psychosomatic symptoms in association with PND were significantly related to the woman's having a negative view of herself in general and of being a gene carrier, a planned pregnancy, high education, a good general knowledge of haemophilia and a guiding philosophy of life. Women with strong negative reactions significantly more often reported signs of depressive mood at follow-up. The results suggest that giving more information and promoting increased knowledge about the disease and the PND procedure will, by itself, not help women to cope better emotionally. Provision of prospective psychosocial support is recommended.}},
  author       = {{Tedgård, U. and Ljung, R. and Mcneil, T.F. and Landegren Tedgård, Eva}},
  issn         = {{1351-8216}},
  keywords     = {{article; clinical article; depression; disease carrier; fetus; fetus blood; hemophilia A; hemophilia B; human; mood; prenatal diagnosis; priority journal}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{2}},
  pages        = {{123--130}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Haemophilia}},
  title        = {{Identifying carriers at high risk for negative reactions when performing prenatal diagnosis of haemophilia}},
  url          = {{http://dx.doi.org/10.1046/j.1365-2516.1997.00093.x}},
  doi          = {{10.1046/j.1365-2516.1997.00093.x}},
  volume       = {{3}},
  year         = {{1997}},
}