Protein Evolution

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2024
Mark Peptidyl-tRNA hydrolase is the nascent chain release factor in bacterial ribosome-associated quality control
Svetlov, Maxim S. ; Dunand, Clémence F. ; Nakamoto, Jose A. ^LU ; Atkinson, Gemma C. ^LU ; Safdari, Haaris A. ; Wilson, Daniel N. ; Vázquez-Laslop, Nora and Mankin, Alexander S. (2024) In Molecular Cell 84(4). p.5-726
- Contribution to journal › Article
Mark A Comprehensive Resource for Exploring Antiphage Defense : DefenseFinder Webservice,Wiki and Databases
Tesson, Florian ; Planel, Rémi ; Egorov, Artyom A. ^LU ; Georjon, Héloïse ; Vaysset, Hugo ; Brancotte, Bryan ; Néron, Bertrand ; Mordret, Ernest ; Atkinson, Gemma Catherine ^LU and Bernheim, Aude , et al. (2024) In Peer Community Journal 4.
- Contribution to journal › Article
Mark The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site
Turnbull, Kathryn ; Paternoga, Helge ; von der Weth, Esther ; Egorov, Artyom A ^LU ; Pochopien, Agnieszka A ; Zhang, Yujie ; Nersisyan, Lilit ; Margus, Tõnu ; Johansson, Marcus J O ^LU and Pelechano, Vicent , et al. (2024) In Nucleic Acids Research 52(19). p.12005-12020
- Contribution to journal › Article
Mark Toxic small alarmone synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr
Kurata, Tatsuaki ^LU ; Takegawa, Masaki ; Ohira, Takayuki ; Syroegin, Egor A ; Atkinson, Gemma C ^LU ; Johansson, Marcus J O ^LU ; Polikanov, Yury S ; Garcia-Pino, Abel ; Suzuki, Tsutomu and Hauryliuk, Vasili ^LU (2024) In Science Advances 10(46).
- Contribution to journal › Article
2023
Mark Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint
Tamman, Hedvig ; Ernits, Karin ^LU ; Roghanian, Mohammad ^LU ; Ainelo, Andres ; Julius, Christina ^LU ; Perrier, Anthony ; Talavera, Ariel ; Ainelo, Hanna ; Dugauquier, Rémy and Zedek, Safia , et al. (2023) In Nature Chemical Biology 19(3). p.334-345
- Contribution to journal › Article
Mark The structure of DarB in complex with RelNTD reveals nonribosomal activation of Rel stringent factors
Ainelo, Andres ; Caballero-Montes, Julien ; Bulvas, Ondřej ; Ernits, Karin ^LU ; Coppieters 't Wallant, Kyo ; Takada, Hiraku ^LU ; Craig, Sophie Z ; Mazzucchelli, Gabriel ; Zedek, Safia and Pichová, Iva , et al. (2023) In Science Advances 9(3). p.1-14
- Contribution to journal › Article
Mark Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria : VmlR2, Ard1 and CplR
Obana, Nozomu ; Takada, Hiraku ^LU ; Crowe-McAuliffe, Caillan ; Iwamoto, Mizuki ; Egorov, Artyom A ^LU ; Wu, Kelvin J Y ; Chiba, Shinobu ; Murina, Victoriia ; Paternoga, Helge and Tresco, Ben I C , et al. (2023) In Nucleic Acids Research 51(9). p.4536-4554
- Contribution to journal › Article
Mark The structural basis of hyperpromiscuity in a core combinatorial network of type II toxin-antitoxin and related phage defense systems
Ernits, Karin ^LU ; Saha, Chayan Kumar ^LU ; Brodiazhenko, Tetiana ; Chouhan, Bhanu ^LU ; Shenoy, Aditi ; Buttress, Jessica A ; Duque-Pedraza, Julián J ^LU ; Bojar, Veda ^LU ; Nakamoto, Jose A ^LU and Kurata, Tatsuaki ^LU , et al. (2023) In Proceedings of the National Academy of Sciences of the United States of America 120(33). p.1-12
- Contribution to journal › Article
Mark The native ABC-F proteins of Staphylococcus aureus do not contribute to intrinsic resistance against ribosome-targeting antibacterial drugs
Galarion, Luiza H. ; Trigwell, James ; Mohamad, Merianne ; Nakamoto, Jose A. ^LU ; Clarke, Justin E. ; Atkinson, Gemma C. ^LU and O'neill, Alex J. (2023) In Journal of Antimicrobial Chemotherapy 78(10). p.2601-2603
- Contribution to journal › Article
Mark uORF4u : a tool for annotation of conserved upstream open reading frames
Egorov, Artyom A. ^LU and Atkinson, Gemma C. ^LU (2023) In Bioinformatics 39(5).
- Contribution to journal › Article